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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
-7.04%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$416M
AUM Growth
+$241M
Cap. Flow
+$269M
Cap. Flow %
64.6%
Top 10 Hldgs %
83.32%
Holding
503
New
3
Increased
27
Reduced
1
Closed
472

Top Buys

Rank Stock Value
1
NVDA icon
NVIDIA
NVDA
+$58.1M
2
AAPL icon
Apple
AAPL
+$50.9M
3
GOOGL icon
Alphabet (Google) Class A
GOOGL
+$44.7M
4
MSFT icon
Microsoft
MSFT
+$42.1M
5
AMZN icon
Amazon
AMZN
+$28.8M

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$102M
2
GOOG icon
Alphabet (Google) Class C
GOOG
+$314K
3
BRK.B icon
Berkshire Hathaway Class B
BRK.B
+$199K
4
JPM icon
JPMorgan Chase
JPM
+$189K
5
LLY icon
Eli Lilly
LLY
+$184K

Sector Composition

Rank Sector Weight
1 Technology 59.32%
2 Communication Services 16.1%
3 Consumer Discretionary 10.79%
4 Financials 0%
5 Healthcare 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
AZO icon
76
AutoZone
AZO
$51.3B
– –
-3
Closed -$10.2K
BA icon
77
Boeing
BA
$169B
– –
-168
Closed -$36.5K
BAC icon
78
Bank of America
BAC
$429B
– –
-1,449
Closed -$79.7K
BALL icon
79
Ball Corp
BALL
$17.5B
– –
-58
Closed -$3.07K
BAX icon
80
Baxter International
BAX
$12.8B
– –
-110
Closed -$2.1K
BBY icon
81
Best Buy
BBY
$19B
– –
-42
Closed -$2.81K
BDX icon
82
Becton Dickinson
BDX
$46.4B
– –
-62
Closed -$12K
BEN icon
83
Franklin Resources
BEN
$16.8B
– –
-66
Closed -$1.58K
BF.B icon
84
Brown-Forman Class B
BF.B
$13.5B
– –
-38
Closed -$990
BG icon
85
Bunge Global
BG
$20.9B
– –
-30
Closed -$2.67K
BIIB icon
86
Biogen
BIIB
$30.9B
– –
-31
Closed -$5.46K
BNY
87
Bank of New York Mellon
BNY
$103B
– –
-151
Closed -$17.5K
BKR icon
88
Baker Hughes
BKR
$58.3B
– –
-213
Closed -$9.7K
BLDR icon
89
Builders FirstSource
BLDR
$7.29B
– –
-24
Closed -$2.47K
BLK icon
90
Blackrock
BLK
$167B
– –
-31
Closed -$33.2K
BMY icon
91
Bristol-Myers Squibb
BMY
$129B
– –
-438
Closed -$23.6K
BR icon
92
Broadridge
BR
$18.4B
– –
-25
Closed -$5.58K
BRK.B icon
93
Berkshire Hathaway Class B
BRK.B
$1.1T
– –
-395
Closed -$199K
BRO icon
94
Brown & Brown
BRO
$25.1B
– –
-63
Closed -$5.02K
BSX icon
95
Boston Scientific
BSX
$68.4B
– –
-319
Closed -$30.4K
BX icon
96
Blackstone
BX
$104B
– –
-159
Closed -$24.5K
BXP icon
97
Boston Properties
BXP
$11.6B
– –
-31
Closed -$2.09K
C icon
98
Citigroup
C
$213B
– –
-386
Closed -$45K
CAG icon
99
Conagra Brands
CAG
$7.42B
– –
-103
Closed -$1.78K
CAH icon
100
Cardinal Health
CAH
$53.7B
– –
-52
Closed -$10.7K
2 3
4
5 6

Similar funds

VM
Venator Management Pittsburgh, Pennsylvania $416M AUM 16.01% 1-Year Est. Return
SCP
Stevens Capital Partners Omaha, Nebraska $416M AUM 18.93% 1-Year Est. Return
SSC
Spruce Street Capital New York $416M AUM
SSC
Syverson Strege & Co West Des Moines, Iowa $416M AUM 21.16% 1-Year Est. Return
CEI
Clark Estates Inc New York $416M AUM 6.04% 1-Year Est. Return
I
InceptionR Lafayette, California $415M AUM 17.85% 1-Year Est. Return
AWCI
Alpine Woods Capital Investors Purchase, New York $417M AUM 26.83% 1-Year Est. Return
BRA
Bender Robert & Associates Pasadena, California $417M AUM 25.02% 1-Year Est. Return

Howard Hughes Medical Institute's Q1 2026 Portfolio in Review

As of Q1 2026, Howard Hughes Medical Institute held 503 positions worth $416M, up 138% from $175M the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Howard Hughes Medical Institute deployed $269M of net new capital in Q1 2026, opening 3 new positions and adding to 27 existing holdings. Its largest new stake was TSMC: 66,773 shares worth $22.6M.

By sector, the portfolio is most concentrated in Technology at 59% of assets, up from 2.5% a quarter earlier, followed by Communication Services and Consumer Discretionary.

On the sell side, the largest reduction was State Street SPDR S&P 500 ETF Trust, an estimated $102M trimmed.

  • Howard Hughes Medical Institute's largest Q1 2026 buy was TSMC: 66,773 shares worth $22.6M.
  • Howard Hughes Medical Institute added most to NVIDIA in Q1 2026, an estimated $58.1M increase.
  • Howard Hughes Medical Institute's biggest Q1 2026 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $102M.
  • Howard Hughes Medical Institute fully exited Alphabet (Google) Class C in Q1 2026, selling an estimated $314K.
  • Howard Hughes Medical Institute's ten largest holdings make up 83% of its $416M portfolio in Q1 2026.
  • Howard Hughes Medical Institute opened 3 new positions and closed 472 in Q1 2026.
  • Howard Hughes Medical Institute's portfolio value rose 138% quarter-over-quarter to $416M.

Based on Howard Hughes Medical Institute's 13F filing for Q1 2026, filed 15 May 2026.