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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
Cap. Flow
+$25.5M
Cap. Flow %
10.17%
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
–
Closed
1

Top Buys

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$15.6M
2
MSFT icon
Microsoft
MSFT
+$700K
3
NVDA icon
NVIDIA
NVDA
+$665K
4
AAPL icon
Apple
AAPL
+$653K
5
AMZN icon
Amazon
AMZN
+$403K

Top Sells

Rank Stock Value
1
BIOA
BioAge Labs
BIOA
+$428K

Sector Composition

Rank Sector Weight
1 Technology 1.55%
2 Financials 0.62%
3 Consumer Discretionary 0.47%
4 Communication Services 0.44%
5 Healthcare 0.42%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
SPY icon
1
State Street SPDR S&P 500 ETF Trust
SPY
$810B
$240M 95.52%
387,885
+27,222
+8% +$15.6M
NVDA icon
2
NVIDIA
NVDA
$5.42T
$835K 0.33%
+5,285
New +$665K
MSFT icon
3
Microsoft
MSFT
$3.71T
$801K 0.32%
+1,611
New +$700K
AAPL icon
4
Apple
AAPL
$4.57T
$663K 0.26%
+3,232
New +$653K
AMZN icon
5
Amazon
AMZN
$2.96T
$447K 0.18%
+2,039
New +$403K
META icon
6
Meta Platforms (Facebook)
META
$1.51T
$349K 0.14%
+473
New +$292K
AVGO icon
7
Broadcom
AVGO
$2.04T
$279K 0.11%
+1,011
New +$220K
GOOGL icon
8
Alphabet (Google) Class A
GOOGL
$4.33T
$222K 0.09%
+1,260
New +$206K
BRK.B icon
9
Berkshire Hathaway Class B
BRK.B
$1.13T
$192K 0.08%
+396
New +$201K
TSLA icon
10
Tesla
TSLA
$1.3T
$191K 0.08%
+601
New +$181K
GOOG icon
11
Alphabet (Google) Class C
GOOG
$4.32T
$181K 0.07%
+1,021
New +$169K
JPM icon
12
JPMorgan Chase
JPM
$950B
$175K 0.07%
+605
New +$154K
LLY icon
13
Eli Lilly
LLY
$1.06T
$133K 0.05%
+170
New +$132K
V icon
14
Visa
V
$677B
$132K 0.05%
+372
New +$130K
NFLX icon
15
Netflix
NFLX
$309B
$123K 0.05%
+920
New +$104K
XOM icon
16
ExxonMobil
XOM
$634B
$102K 0.04%
+943
New +$101K
MA icon
17
Mastercard
MA
$493B
$98.9K 0.04%
+176
New +$97.3K
COST icon
18
Costco
COST
$420B
$94K 0.04%
+95
New +$94.4K
WMT icon
19
Walmart Inc
WMT
$890B
$91.6K 0.04%
+937
New +$89.3K
PG icon
20
Procter & Gamble
PG
$339B
$80.6K 0.03%
+506
New +$82.6K
JNJ icon
21
Johnson & Johnson
JNJ
$625B
$79.4K 0.03%
+520
New +$79.9K
HD icon
22
Home Depot
HD
$355B
$78.5K 0.03%
+214
New +$77.4K
ORCL icon
23
Oracle
ORCL
$423B
$76.5K 0.03%
+350
New +$56.5K
ABBV icon
24
AbbVie
ABBV
$435B
$70.7K 0.03%
+381
New +$70.8K
BAC icon
25
Bank of America
BAC
$442B
$67.8K 0.03%
+1,432
New +$60.2K
1
2 3 4 5

Similar funds

VM
Venator Management Pittsburgh, Pennsylvania $416M AUM 16.01% 1-Year Est. Return
SCP
Stevens Capital Partners Omaha, Nebraska $416M AUM 18.93% 1-Year Est. Return
SSC
Spruce Street Capital New York $416M AUM
I
InceptionR Lafayette, California $415M AUM 17.85% 1-Year Est. Return
SCMS
Serenity Capital Management (Singapore) Singapore $414M AUM 16.41% 1-Year Est. Return
ACM
Alight Capital Management New York $417M AUM 98.18% 1-Year Est. Return
MCM
Millstreet Capital Management Boston, Massachusetts $418M AUM 80.77% 1-Year Est. Return
MIA
Milestone Investment Advisors Middleton, Wisconsin $414M AUM 12.76% 1-Year Est. Return

Howard Hughes Medical Institute's Q2 2025 Portfolio in Review

As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.

Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.

By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.

On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.

  • Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
  • Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
  • Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
  • Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
  • Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
  • Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.

Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.