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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
+2.49%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$175M
AUM Growth
+$4.07M
Cap. Flow
+$32K
Cap. Flow %
0.02%
Top 10 Hldgs %
95.56%
Holding
506
New
6
Increased
70
Reduced
86
Closed
6

Top Buys

Rank Stock Value
1
CRH icon
CRH
CRH
+$17.2K
2
CVNA icon
Carvana
CVNA
+$11.2K
3
ARES icon
Ares Management
ARES
+$6.86K
4
FIX icon
Comfort Systems
FIX
+$6.46K
5
SNDK
Sandisk
SNDK
+$6.01K

Top Sells

Rank Stock Value
1
K
Kellanova
K
+$4.76K
2
DD icon
DuPont de Nemours
DD
+$4.72K
3
NVDA icon
NVIDIA
NVDA
+$3.54K
4
IPG
Interpublic Group of Companies
IPG
+$2.21K
5
LKQ icon
LKQ Corp
LKQ
+$1.71K

Sector Composition

Rank Sector Weight
1 Technology 2.52%
2 Financials 0.95%
3 Communication Services 0.78%
4 Consumer Discretionary 0.76%
5 Healthcare 0.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
SPY icon
1
State Street SPDR S&P 500 ETF Trust
SPY
$810B
$162M 92.85%
237,885
– –
NVDA icon
2
NVIDIA
NVDA
$5.29T
$974K 0.56%
5,221
-19
-0.4% -$3.54K
AAPL icon
3
Apple
AAPL
$4.46T
$866K 0.5%
3,184
-4
-0.1% -$1.07K
MSFT icon
4
Microsoft
MSFT
$3.78T
$774K 0.44%
1,600
+3
+0.2% +$1.5K
AMZN icon
5
Amazon
AMZN
$3T
$483K 0.28%
2,093
+9
+0.4% +$2.06K
GOOGL icon
6
Alphabet (Google) Class A
GOOGL
$4.33T
$391K 0.22%
1,250
– –
AVGO icon
7
Broadcom
AVGO
$2.02T
$352K 0.2%
1,016
+5
+0.5% +$1.79K
GOOG icon
8
Alphabet (Google) Class C
GOOG
$4.31T
$314K 0.18%
1,000
-3
-0.3% -$859
META icon
9
Meta Platforms (Facebook)
META
$1.52T
$310K 0.18%
469
+3
+0.6% +$2K
TSLA icon
10
Tesla
TSLA
$1.3T
$271K 0.16%
603
+1
+0.2% +$443
BRK.B icon
11
Berkshire Hathaway Class B
BRK.B
$1.15T
$199K 0.11%
395
+1
+0.3% +$498
JPM icon
12
JPMorgan Chase
JPM
$951B
$189K 0.11%
588
-3
-0.5% -$929
LLY icon
13
Eli Lilly
LLY
$1.08T
$184K 0.11%
171
+1
+0.6% +$956
V icon
14
Visa
V
$673B
$128K 0.07%
364
-1
-0.3% -$341
XOM icon
15
ExxonMobil
XOM
$656B
$110K 0.06%
912
-4
-0.4% -$464
JNJ icon
16
Johnson & Johnson
JNJ
$627B
$108K 0.06%
520
+2
+0.4% +$395
WMT icon
17
Walmart Inc
WMT
$889B
$106K 0.06%
947
+5
+0.5% +$537
MA icon
18
Mastercard
MA
$492B
$101K 0.06%
177
– –
PLTR icon
19
Palantir
PLTR
$426B
$87.1K 0.05%
490
+2
+0.4% +$362
ABBV icon
20
AbbVie
ABBV
$433B
$87.1K 0.05%
381
+1
+0.3% +$228
NFLX icon
21
Netflix
NFLX
$315B
$85.6K 0.05%
913
-7
-0.8% -$755
COST icon
22
Costco
COST
$419B
$81.9K 0.05%
95
– –
BAC icon
23
Bank of America
BAC
$445B
$79.7K 0.05%
1,449
-14
-1% -$740
AMD icon
24
Advanced Micro Devices
AMD
$777B
$75K 0.04%
350
+1
+0.3% +$225
HD icon
25
Home Depot
HD
$347B
$73.6K 0.04%
214
– –
1
2 3 4 5

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VM
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SSC
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I
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ACM
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MCM
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MIA
Milestone Investment Advisors Middleton, Wisconsin $414M AUM 12.76% 1-Year Est. Return
FFA
Florida Financial Advisors Tampa, Florida $418M AUM 41.28% 1-Year Est. Return
SP
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Howard Hughes Medical Institute's Q4 2025 Portfolio in Review

As of Q4 2025, Howard Hughes Medical Institute held 506 positions worth $175M, up 2.4% from $171M the previous quarter. Its ten largest holdings account for 96% of the portfolio.

Trading was light in Q4 2025: portfolio turnover was 2.4%. Howard Hughes Medical Institute opened 6 new positions and exited 6, leaving the 506-position portfolio largely intact.

By sector, the portfolio is most concentrated in Technology at 2.5% of assets, down from 2.6% a quarter earlier, followed by Financials and Communication Services.

  • Howard Hughes Medical Institute's largest Q4 2025 buy was CRH: 144 shares worth $18K.
  • Howard Hughes Medical Institute added most to Omnicom Group in Q4 2025, an estimated $2.06K increase.
  • Howard Hughes Medical Institute's biggest Q4 2025 reduction was DuPont de Nemours, cutting an estimated $4.72K.
  • Howard Hughes Medical Institute fully exited Kellanova in Q4 2025, selling an estimated $4.76K.
  • Howard Hughes Medical Institute's ten largest holdings make up 96% of its $175M portfolio in Q4 2025.
  • Howard Hughes Medical Institute opened 6 new positions and closed 6 in Q4 2025.
  • Howard Hughes Medical Institute's portfolio value rose 2.4% quarter-over-quarter to $175M.

Based on Howard Hughes Medical Institute's 13F filing for Q4 2025, filed 17 Feb 2026.