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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
-7.04%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$416M
AUM Growth
+$241M
Cap. Flow
+$269M
Cap. Flow %
64.6%
Top 10 Hldgs %
83.32%
Holding
503
New
3
Increased
27
Reduced
1
Closed
472

Top Buys

Rank Stock Value
1
NVDA icon
NVIDIA
NVDA
+$58.1M
2
AAPL icon
Apple
AAPL
+$50.9M
3
GOOGL icon
Alphabet (Google) Class A
GOOGL
+$44.7M
4
MSFT icon
Microsoft
MSFT
+$42.1M
5
AMZN icon
Amazon
AMZN
+$28.8M

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$102M
2
GOOG icon
Alphabet (Google) Class C
GOOG
+$314K
3
BRK.B icon
Berkshire Hathaway Class B
BRK.B
+$199K
4
JPM icon
JPMorgan Chase
JPM
+$189K
5
LLY icon
Eli Lilly
LLY
+$184K

Sector Composition

Rank Sector Weight
1 Technology 59.32%
2 Communication Services 16.1%
3 Consumer Discretionary 10.79%
4 Financials 0%
5 Healthcare 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CARR icon
101
Carrier Global
CARR
$50.6B
– –
-171
Closed -$9.04K
CAT icon
102
Caterpillar
CAT
$373B
– –
-101
Closed -$57.9K
CB icon
103
Chubb
CB
$135B
– –
-79
Closed -$24.7K
CBOE icon
104
Cboe Global Markets
CBOE
$31B
– –
-22
Closed -$5.52K
CBRE icon
105
CBRE Group
CBRE
$43.8B
– –
-63
Closed -$10.1K
CCI icon
106
Crown Castle
CCI
$33.4B
– –
-93
Closed -$8.27K
CCL icon
107
Carnival Corporation Ltd
CCL
$38B
– –
-233
Closed -$7.12K
CDNS icon
108
Cadence Design Systems
CDNS
$91.7B
– –
-59
Closed -$18.4K
CDW icon
109
CDW
CDW
$18.6B
– –
-28
Closed -$3.81K
CEG icon
110
Constellation Energy
CEG
$94.1B
– –
-67
Closed -$23.7K
CF icon
111
CF Industries
CF
$19.3B
– –
-34
Closed -$2.63K
CFG icon
112
Citizens Financial Group
CFG
$30.3B
– –
-93
Closed -$5.43K
CHD icon
113
Church & Dwight Co
CHD
$23.1B
– –
-52
Closed -$4.36K
CHRW icon
114
C.H. Robinson
CHRW
$17.3B
– –
-25
Closed -$4.02K
CHTR icon
115
Charter Communications
CHTR
$16.9B
– –
-19
Closed -$3.97K
CI icon
116
Cigna
CI
$76.1B
– –
-58
Closed -$16K
CINF icon
117
Cincinnati Financial
CINF
$26.8B
– –
-33
Closed -$5.39K
CL icon
118
Colgate-Palmolive
CL
$73.3B
– –
-174
Closed -$13.7K
CLX icon
119
Clorox
CLX
$11.7B
– –
-26
Closed -$2.62K
CMCSA icon
120
Comcast
CMCSA
$84B
– –
-783
Closed -$23.4K
CME icon
121
CME Group
CME
$96.1B
– –
-77
Closed -$21K
CMG icon
122
Chipotle Mexican Grill
CMG
$49.4B
– –
-284
Closed -$10.5K
CMI icon
123
Cummins
CMI
$87.3B
– –
-29
Closed -$14.8K
CMS icon
124
CMS Energy
CMS
$22.7B
– –
-65
Closed -$4.54K
CNC icon
125
Centene
CNC
$30.1B
– –
-101
Closed -$4.16K
3 4
5
6 7

Similar funds

VM
Venator Management Pittsburgh, Pennsylvania $416M AUM 16.01% 1-Year Est. Return
SCP
Stevens Capital Partners Omaha, Nebraska $416M AUM 18.93% 1-Year Est. Return
SSC
Spruce Street Capital New York $416M AUM
SSC
Syverson Strege & Co West Des Moines, Iowa $416M AUM 21.16% 1-Year Est. Return
CEI
Clark Estates Inc New York $416M AUM 6.04% 1-Year Est. Return
I
InceptionR Lafayette, California $415M AUM 17.85% 1-Year Est. Return
AWCI
Alpine Woods Capital Investors Purchase, New York $417M AUM 26.83% 1-Year Est. Return
SCMS
Serenity Capital Management (Singapore) Singapore $414M AUM 16.41% 1-Year Est. Return

Howard Hughes Medical Institute's Q1 2026 Portfolio in Review

As of Q1 2026, Howard Hughes Medical Institute held 503 positions worth $416M, up 138% from $175M the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Howard Hughes Medical Institute deployed $269M of net new capital in Q1 2026, opening 3 new positions and adding to 27 existing holdings. Its largest new stake was TSMC: 66,773 shares worth $22.6M.

By sector, the portfolio is most concentrated in Technology at 59% of assets, up from 2.5% a quarter earlier, followed by Communication Services and Consumer Discretionary.

On the sell side, the largest reduction was State Street SPDR S&P 500 ETF Trust, an estimated $102M trimmed.

  • Howard Hughes Medical Institute's largest Q1 2026 buy was TSMC: 66,773 shares worth $22.6M.
  • Howard Hughes Medical Institute added most to NVIDIA in Q1 2026, an estimated $58.1M increase.
  • Howard Hughes Medical Institute's biggest Q1 2026 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $102M.
  • Howard Hughes Medical Institute fully exited Alphabet (Google) Class C in Q1 2026, selling an estimated $314K.
  • Howard Hughes Medical Institute's ten largest holdings make up 83% of its $416M portfolio in Q1 2026.
  • Howard Hughes Medical Institute opened 3 new positions and closed 472 in Q1 2026.
  • Howard Hughes Medical Institute's portfolio value rose 138% quarter-over-quarter to $416M.

Based on Howard Hughes Medical Institute's 13F filing for Q1 2026, filed 15 May 2026.