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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
-7.04%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$416M
AUM Growth
+$241M
Cap. Flow
+$269M
Cap. Flow %
64.6%
Top 10 Hldgs %
83.32%
Holding
503
New
3
Increased
27
Reduced
1
Closed
472

Top Buys

Rank Stock Value
1
NVDA icon
NVIDIA
NVDA
+$58.1M
2
AAPL icon
Apple
AAPL
+$50.9M
3
GOOGL icon
Alphabet (Google) Class A
GOOGL
+$44.7M
4
MSFT icon
Microsoft
MSFT
+$42.1M
5
AMZN icon
Amazon
AMZN
+$28.8M

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$102M
2
GOOG icon
Alphabet (Google) Class C
GOOG
+$314K
3
BRK.B icon
Berkshire Hathaway Class B
BRK.B
+$199K
4
JPM icon
JPMorgan Chase
JPM
+$189K
5
LLY icon
Eli Lilly
LLY
+$184K

Sector Composition

Rank Sector Weight
1 Technology 59.32%
2 Communication Services 16.1%
3 Consumer Discretionary 10.79%
4 Financials 0%
5 Healthcare 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ALGN icon
51
Align Technology
ALGN
$12.9B
– –
-15
Closed -$2.34K
ALL icon
52
Allstate
ALL
$70.6B
– –
-57
Closed -$11.9K
ALLE icon
53
Allegion
ALLE
$13.5B
– –
-18
Closed -$2.87K
AMCR icon
54
Amcor
AMCR
$21.2B
– –
-99
Closed -$4.14K
AME icon
55
Ametek
AME
$53.9B
– –
-49
Closed -$10.1K
AMGN icon
56
Amgen
AMGN
$209B
– –
-116
Closed -$38K
AMP icon
57
Ameriprise Financial
AMP
$47.8B
– –
-20
Closed -$9.81K
AMT icon
58
American Tower
AMT
$83.5B
– –
-100
Closed -$17.6K
ANET icon
59
Arista Networks
ANET
$199B
– –
-222
Closed -$29.1K
AON icon
60
Aon
AON
$80.6B
– –
-46
Closed -$16.2K
AOS icon
61
A.O. Smith
AOS
$8.55B
– –
-25
Closed -$1.67K
APA icon
62
APA Corp
APA
$13B
– –
-77
Closed -$1.88K
APD icon
63
Air Products & Chemicals
APD
$65.5B
– –
-48
Closed -$11.9K
APH icon
64
Amphenol
APH
$185B
– –
-263
Closed -$35.5K
APO icon
65
Apollo Global Management
APO
$69B
– –
-99
Closed -$14.3K
APP icon
66
Applovin
APP
$134B
– –
-58
Closed -$39.1K
APTV icon
67
Aptiv
APTV
$12.3B
– –
-47
Closed -$3.58K
ARE icon
68
Alexandria Real Estate Equities
ARE
$9.37B
– –
-33
Closed -$1.61K
ARES icon
69
Ares Management
ARES
$28.1B
– –
-44
Closed -$7.11K
ATO icon
70
Atmos Energy
ATO
$29.7B
– –
-34
Closed -$5.7K
AVB icon
71
AvalonBay Communities
AVB
$27.5B
– –
-30
Closed -$5.44K
AVY icon
72
Avery Dennison
AVY
$12.8B
– –
-17
Closed -$3.09K
AWK icon
73
American Water Works
AWK
$27B
– –
-42
Closed -$5.48K
AXON
74
Axon Enterprise
AXON
$42.8B
– –
-16
Closed -$9.09K
AXP icon
75
American Express
AXP
$224B
– –
-116
Closed -$42.9K
1 2
3
4 5

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VM
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SCP
Stevens Capital Partners Omaha, Nebraska $416M AUM 18.93% 1-Year Est. Return
SSC
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SSC
Syverson Strege & Co West Des Moines, Iowa $416M AUM 21.16% 1-Year Est. Return
CEI
Clark Estates Inc New York $416M AUM 6.04% 1-Year Est. Return
I
InceptionR Lafayette, California $415M AUM 17.85% 1-Year Est. Return
AWCI
Alpine Woods Capital Investors Purchase, New York $417M AUM 26.83% 1-Year Est. Return
BRA
Bender Robert & Associates Pasadena, California $417M AUM 25.02% 1-Year Est. Return

Howard Hughes Medical Institute's Q1 2026 Portfolio in Review

As of Q1 2026, Howard Hughes Medical Institute held 503 positions worth $416M, up 138% from $175M the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Howard Hughes Medical Institute deployed $269M of net new capital in Q1 2026, opening 3 new positions and adding to 27 existing holdings. Its largest new stake was TSMC: 66,773 shares worth $22.6M.

By sector, the portfolio is most concentrated in Technology at 59% of assets, up from 2.5% a quarter earlier, followed by Communication Services and Consumer Discretionary.

On the sell side, the largest reduction was State Street SPDR S&P 500 ETF Trust, an estimated $102M trimmed.

  • Howard Hughes Medical Institute's largest Q1 2026 buy was TSMC: 66,773 shares worth $22.6M.
  • Howard Hughes Medical Institute added most to NVIDIA in Q1 2026, an estimated $58.1M increase.
  • Howard Hughes Medical Institute's biggest Q1 2026 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $102M.
  • Howard Hughes Medical Institute fully exited Alphabet (Google) Class C in Q1 2026, selling an estimated $314K.
  • Howard Hughes Medical Institute's ten largest holdings make up 83% of its $416M portfolio in Q1 2026.
  • Howard Hughes Medical Institute opened 3 new positions and closed 472 in Q1 2026.
  • Howard Hughes Medical Institute's portfolio value rose 138% quarter-over-quarter to $416M.

Based on Howard Hughes Medical Institute's 13F filing for Q1 2026, filed 15 May 2026.