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HHMI

Howard Hughes Medical Institute Portfolio holdings

AUM $416M
1-Year Est. Return 13.82%
This Fund
S&P 500
This Quarter Est. Return
-7.04%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$416M
AUM Growth
+$241M
Cap. Flow
+$269M
Cap. Flow %
64.6%
Top 10 Hldgs %
83.32%
Holding
503
New
3
Increased
27
Reduced
1
Closed
472

Top Buys

Rank Stock Value
1
NVDA icon
NVIDIA
NVDA
+$58.1M
2
AAPL icon
Apple
AAPL
+$50.9M
3
GOOGL icon
Alphabet (Google) Class A
GOOGL
+$44.7M
4
MSFT icon
Microsoft
MSFT
+$42.1M
5
AMZN icon
Amazon
AMZN
+$28.8M

Top Sells

Rank Stock Value
1
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$102M
2
GOOG icon
Alphabet (Google) Class C
GOOG
+$314K
3
BRK.B icon
Berkshire Hathaway Class B
BRK.B
+$199K
4
JPM icon
JPMorgan Chase
JPM
+$189K
5
LLY icon
Eli Lilly
LLY
+$184K

Sector Composition

Rank Sector Weight
1 Technology 59.32%
2 Communication Services 16.1%
3 Consumer Discretionary 10.79%
4 Financials 0%
5 Healthcare 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CRM icon
26
Salesforce
CRM
$154B
$2.35M 0.57%
12,612
+12,407
+6,052% +$2.57M
UBER icon
27
Uber
UBER
$145B
$2.08M 0.5%
28,895
+28,448
+6,364% +$2.19M
QCOM icon
28
Qualcomm
QCOM
$164B
$1.91M 0.46%
14,838
+14,606
+6,296% +$2.13M
BKNG icon
29
Booking.com
BKNG
$156B
$1.87M 0.45%
11,100
+10,925
+6,243% +$2.01M
ACN icon
30
Accenture
ACN
$106B
$1.71M 0.41%
8,607
+8,473
+6,323% +$1.97M
INTU icon
31
Intuit
INTU
$91.1B
$1.64M 0.39%
3,794
+3,734
+6,223% +$1.78M
A icon
32
Agilent Technologies
A
$39.6B
– –
-61
Closed -$8.3K
ABBV icon
33
AbbVie
ABBV
$465B
– –
-381
Closed -$87.1K
ABNB icon
34
Airbnb
ABNB
$90.8B
– –
-92
Closed -$12.5K
ABT icon
35
Abbott
ABT
$187B
– –
-375
Closed -$47K
ACGL icon
36
Arch Capital
ACGL
$35.7B
– –
-78
Closed -$7.48K
ADBE icon
37
Adobe
ADBE
$105B
– –
-91
Closed -$31.8K
ADI icon
38
Analog Devices
ADI
$172B
– –
-106
Closed -$28.7K
ADM icon
39
Archer Daniels Midland
ADM
$38.7B
– –
-103
Closed -$5.92K
ADP icon
40
Automatic Data Processing
ADP
$109B
– –
-87
Closed -$22.4K
ADSK icon
41
Autodesk
ADSK
$51.8B
– –
-46
Closed -$13.6K
AEE icon
42
Ameren
AEE
$30.4B
– –
-58
Closed -$5.79K
AEP icon
43
American Electric Power
AEP
$70.4B
– –
-115
Closed -$13.3K
AES icon
44
AES
AES
$10.6B
– –
-153
Closed -$2.19K
AFL icon
45
Aflac
AFL
$65.5B
– –
-102
Closed -$11.2K
AIG icon
46
American International
AIG
$42.5B
– –
-117
Closed -$10K
AIZ icon
47
Assurant
AIZ
$13.9B
– –
-11
Closed -$2.65K
AJG icon
48
Arthur J. Gallagher & Co
AJG
$69.1B
– –
-55
Closed -$14.2K
AKAM icon
49
Akamai
AKAM
$15.6B
– –
-31
Closed -$2.71K
ALB icon
50
Albemarle
ALB
$13.4B
– –
-25
Closed -$3.54K
1
2
3 4 5

Similar funds

VM
Venator Management Pittsburgh, Pennsylvania $416M AUM 16.01% 1-Year Est. Return
SCP
Stevens Capital Partners Omaha, Nebraska $416M AUM 18.93% 1-Year Est. Return
SSC
Spruce Street Capital New York $416M AUM
SSC
Syverson Strege & Co West Des Moines, Iowa $416M AUM 21.16% 1-Year Est. Return
CEI
Clark Estates Inc New York $416M AUM 6.04% 1-Year Est. Return
I
InceptionR Lafayette, California $415M AUM 17.85% 1-Year Est. Return
AWCI
Alpine Woods Capital Investors Purchase, New York $417M AUM 26.83% 1-Year Est. Return
BRA
Bender Robert & Associates Pasadena, California $417M AUM 25.02% 1-Year Est. Return

Howard Hughes Medical Institute's Q1 2026 Portfolio in Review

As of Q1 2026, Howard Hughes Medical Institute held 503 positions worth $416M, up 138% from $175M the previous quarter. Its ten largest holdings account for 83% of the portfolio.

Howard Hughes Medical Institute deployed $269M of net new capital in Q1 2026, opening 3 new positions and adding to 27 existing holdings. Its largest new stake was TSMC: 66,773 shares worth $22.6M.

By sector, the portfolio is most concentrated in Technology at 59% of assets, up from 2.5% a quarter earlier, followed by Communication Services and Consumer Discretionary.

On the sell side, the largest reduction was State Street SPDR S&P 500 ETF Trust, an estimated $102M trimmed.

  • Howard Hughes Medical Institute's largest Q1 2026 buy was TSMC: 66,773 shares worth $22.6M.
  • Howard Hughes Medical Institute added most to NVIDIA in Q1 2026, an estimated $58.1M increase.
  • Howard Hughes Medical Institute's biggest Q1 2026 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $102M.
  • Howard Hughes Medical Institute fully exited Alphabet (Google) Class C in Q1 2026, selling an estimated $314K.
  • Howard Hughes Medical Institute's ten largest holdings make up 83% of its $416M portfolio in Q1 2026.
  • Howard Hughes Medical Institute opened 3 new positions and closed 472 in Q1 2026.
  • Howard Hughes Medical Institute's portfolio value rose 138% quarter-over-quarter to $416M.

Based on Howard Hughes Medical Institute's 13F filing for Q1 2026, filed 15 May 2026.