Group One Trading’s Structure Therapeutics GPCR Stock Holding History

Group One Trading’s Portfolio GPCR Stock Details GPCR Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$622K	Sell	12,900 -32,800	-72%	-$2.24M	﹤0.01%	3148
2025 Q4	$3.18M	Sell	45,700 -34,300	-43%	-$1.4M	0.01%	1863
2025 Q3	$2.24M	Buy	80,000 +20,800	+35%	+$414K	﹤0.01%	2200
2025 Q2	$1.23M	Sell	59,200 -5,300	-8%	-$117K	﹤0.01%	2580
2025 Q1	$1.12M	Buy	64,500 +25,800	+67%	+$632K	﹤0.01%	2364
2024 Q4	$1.05M	Sell	38,700 -13,100	-25%	-$465K	﹤0.01%	2536
2024 Q3	$2.27M	Buy	51,800 +6,600	+15%	+$255K	0.01%	1626
2024 Q2	$1.78M	Buy	45,200 +37,100	+458%	+$1.52M	0.01%	1548
2024 Q1	$347K	Sell	8,100 -10,200	-56%	-$430K	﹤0.01%	3081
2023 Q4	$746K	Buy	+18,300	New	+$1.05M	﹤0.01%	2729

Other funds holding GPCR

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return

DTC

Deep Track Capital Greenwich, Connecticut $6.12B AUM 144% 1-Year Est. Return

BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return

Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return

T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return

Principal Financial Group Des Moines, Iowa $187B AUM 18.48% 1-Year Est. Return

DCM

Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return

Group One Trading's GPCR Position: Q4 2025 in Review

Group One Trading sold out of Structure Therapeutics (GPCR) in Q4 2025, closing a stake of 986 shares — an estimated $40.3K sold.

Group One Trading first reported a position in GPCR in Q4 2023 and held it in 7 quarters. The position peaked at $847K in Q1 2025. 197 funds tracked by Wall St. Rank hold GPCR as of Q4 2025.

Group One Trading reported no remaining Structure Therapeutics position as of Q4 2025 after selling out during the quarter.
Group One Trading sold 986 Structure Therapeutics shares in Q4 2025, an estimated $40.3K.
Group One Trading first reported a position in Structure Therapeutics in Q4 2023 and held it in 7 quarters.
Group One Trading's Structure Therapeutics position peaked at $847K in Q1 2025.
197 funds tracked by Wall St. Rank held Structure Therapeutics as of Q4 2025.

Based on Group One Trading's 13F filing for Q4 2025, filed 12 Feb 2026.