David Shaw’s Zymeworks ZYME Stock Holding History
Bought
Maintained
Sold
| Quarter | Market Value | Status | Shares |
Change in Stake | Trade Value | Portfolio Weight | Portfolio Position | |
|---|---|---|---|---|---|---|---|---|
|
2026
Q2 | $3.79M | Sell |
144,807
-90,814
| -39% | -$2.31M | ﹤0.01% | 2650 |
|
|
2026
Q1 | $5.9M | Buy |
235,621
+11,835
| +5% | +$280K | ﹤0.01% | 2057 |
|
|
2025
Q4 | $5.89M | Buy |
223,786
+96,863
| +76% | +$2.11M | ﹤0.01% | 2175 |
|
|
2025
Q3 | $2.17M | Sell |
126,923
-128,368
| -50% | -$1.84M | ﹤0.01% | 2912 |
|
|
2025
Q2 | $3.2M | Buy |
255,291
+192,192
| +305% | +$2.29M | ﹤0.01% | 2377 |
|
|
2025
Q1 | $752K | Buy |
63,099
+42,259
| +203% | +$576K | ﹤0.01% | 3268 |
|
|
2024
Q4 | $305K | Sell |
20,840
-942
| -4% | -$13.2K | ﹤0.01% | 3879 |
|
|
2024
Q3 | $273K | Sell |
21,782
-21,974
| -50% | -$239K | ﹤0.01% | 4020 |
|
|
2024
Q2 | $372K | Buy |
43,756
+16,643
| +61% | +$148K | ﹤0.01% | 3786 |
|
|
2024
Q1 | $285K | Buy |
+27,113
| New | +$301K | ﹤0.01% | 3753 |
|
|
2023
Q4 | – | Sell |
-65,068
| Closed | -$413K | – | 4673 |
|
|
2023
Q3 | $413K | Buy |
65,068
+15,714
| +32% | +$116K | ﹤0.01% | 3498 |
|
|
2023
Q2 | $426K | Buy |
+49,354
| New | +$442K | ﹤0.01% | 3481 |
|
|
2023
Q1 | – | Sell |
-369,187
| Closed | -$2.9M | – | 4929 |
|
|
2022
Q4 | $2.9M | Buy |
369,187
+280,710
| +317% | +$1.97M | ﹤0.01% | 2618 |
|
|
2022
Q3 | $544K | Buy |
88,477
+66,567
| +304% | +$401K | ﹤0.01% | 3992 |
|
|
2022
Q2 | $116K | Sell |
21,910
-415,581
| -95% | -$2.51M | ﹤0.01% | 4699 |
|
|
2022
Q1 | $2.87M | Buy |
437,491
+405,408
| +1,264% | +$3.61M | ﹤0.01% | 2947 |
|
|
2021
Q4 | $526K | Buy |
32,083
+23,836
| +289% | +$497K | ﹤0.01% | 4375 |
|
|
2021
Q3 | $239K | Sell |
8,247
-537
| -6% | -$17.9K | ﹤0.01% | 4485 |
|
|
2021
Q2 | $305K | Sell |
8,784
-10,558
| -55% | -$335K | ﹤0.01% | 4271 |
|
|
2021
Q1 | $611K | Sell |
19,342
-48,944
| -72% | -$1.99M | ﹤0.01% | 3408 |
|
|
2020
Q4 | $3.23M | Sell |
68,286
-58,538
| -46% | -$2.72M | ﹤0.01% | 2213 |
|
|
2020
Q3 | $5.91M | Sell |
126,824
-136,862
| -52% | -$4.7M | 0.01% | 1578 |
|
|
2020
Q2 | $9.51M | Sell |
263,686
-2,823
| -1% | -$104K | 0.01% | 1212 |
|
|
2020
Q1 | $9.45M | Sell |
266,509
-275,161
| -51% | -$11.3M | 0.01% | 1030 |
|
|
2019
Q4 | $24.6M | Buy |
541,670
+144,961
| +37% | +$5.27M | 0.03% | 706 |
|
|
2019
Q3 | $9.84M | Buy |
396,709
+136,528
| +52% | +$3.42M | 0.01% | 1173 |
|
|
2019
Q2 | $5.72M | Buy |
+260,181
| New | +$4.78M | 0.01% | 1499 |
|
|
2018
Q3 | – | Sell |
-26,621
| Closed | -$393K | – | 4020 |
|
|
2018
Q2 | $393K | Buy |
+26,621
| New | +$412K | ﹤0.01% | 3246 |
|
Other funds holding ZYME
EC
RCMNY
PA
BI
NI
David Shaw's ZYME Position: Q2 2026 in Review
David Shaw reduced its Zymeworks (ZYME) stake by 39% in Q2 2026, selling an estimated $2.31M and leaving 144,807 shares worth $3.79M. The position accounts for ﹤0.01% of the portfolio, ranked #2650.
David Shaw first reported a position in ZYME in Q2 2018 and has held it in 28 quarters since. The position peaked at $24.6M in Q4 2019. 201 funds tracked by Wall St. Rank hold ZYME as of Q2 2026.
- David Shaw held 144,807 shares of Zymeworks worth $3.79M as of Q2 2026.
- David Shaw sold 90,814 Zymeworks shares in Q2 2026, an estimated $2.31M.
- Zymeworks made up ﹤0.01% of David Shaw's portfolio in Q2 2026, its #2650 holding.
- David Shaw first reported a position in Zymeworks in Q2 2018 and has held it in 28 quarters since.
- David Shaw's Zymeworks position peaked at $24.6M in Q4 2019.
- 201 funds tracked by Wall St. Rank held Zymeworks as of Q2 2026.
Based on D.E. Shaw & Co's 13F filing for Q2 2026, filed 14 Aug 2026.