David Shaw’s Arrowhead Research ARWR Stock Holding History

David Shaw’s Portfolio ARWR Stock Details ARWR Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q3	–	Sell	-58,500	Closed	-$924K	–	4547
2025 Q2	$924K	Buy	58,500 +36,900	+171%	+$529K	﹤0.01%	3291
2025 Q1	$275K	Buy	+21,600	New	+$393K	﹤0.01%	3800
2024 Q4	–	Sell	-11,100	Closed	-$215K	–	4397
2024 Q3	$215K	Buy	+11,100	New	+$271K	﹤0.01%	4121
2022 Q1	–	Sell	-10,000	Closed	-$663K	–	5510
2021 Q4	$663K	Hold	10,000	–	–	﹤0.01%	4230
2021 Q3	$624K	Hold	10,000	–	–	﹤0.01%	3943
2021 Q2	$828K	Hold	10,000	–	–	﹤0.01%	3695
2021 Q1	$663K	Hold	10,000	–	–	﹤0.01%	3371
2020 Q4	$767K	Hold	10,000	–	–	﹤0.01%	3188
2020 Q3	$431K	Sell	10,000 -24,900	-71%	-$1.07M	﹤0.01%	3295
2020 Q2	$1.51M	Buy	34,900 +14,900	+75%	+$526K	﹤0.01%	2628
2020 Q1	$575K	Hold	20,000	–	–	﹤0.01%	3137
2019 Q4	$1.27M	Buy	+20,000	New	+$992K	﹤0.01%	2810
2014 Q2	–	Sell	-33,500	Closed	-$550K	–	4167
2014 Q1	$550K	Buy	+33,500	New	+$588K	﹤0.01%	3517

Other funds holding ARWR

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Norges Bank Oslo, Norway $1T AUM

Invesco Atlanta, Georgia $1.26T AUM 61.52% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

FAM

Fred Alger Management New York $30B AUM 76.99% 1-Year Est. Return

David Shaw's ARWR Position: Q2 2026 in Review

David Shaw reduced its Arrowhead Research (ARWR) stake by 64% in Q2 2026, selling an estimated $55.6M and leaving 431,560 shares worth $35.2M. The position accounts for 0.02% of the portfolio, ranked #954.

David Shaw first reported a position in ARWR in Q1 2014 and has held it in 37 quarters since. The position peaked at $74.2M in Q1 2026. 498 funds tracked by Wall St. Rank hold ARWR as of Q2 2026.

David Shaw held 431,560 shares of Arrowhead Research worth $35.2M as of Q2 2026.
David Shaw sold 752,278 Arrowhead Research shares in Q2 2026, an estimated $55.6M.
Arrowhead Research made up 0.02% of David Shaw's portfolio in Q2 2026, its #954 holding.
David Shaw first reported a position in Arrowhead Research in Q1 2014 and has held it in 37 quarters since.
David Shaw's Arrowhead Research position peaked at $74.2M in Q1 2026.
498 funds tracked by Wall St. Rank held Arrowhead Research as of Q2 2026.

Based on D.E. Shaw & Co's 13F filing for Q2 2026, filed 14 Aug 2026.