David Shaw’s Arrowhead Research ARWR Stock Holding History

David Shaw’s Portfolio ARWR Stock Details ARWR Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	–	Sell	-9,000	Closed	-$564K	–	4868
2026 Q1	$564K	Sell	9,000 -9,000	-50%	-$570K	﹤0.01%	3786
2025 Q4	$1.2M	Buy	+18,000	New	+$882K	﹤0.01%	3423
2025 Q3	–	Sell	-47,300	Closed	-$747K	–	4546
2025 Q2	$747K	Buy	+47,300	New	+$679K	﹤0.01%	3431
2021 Q1	–	Sell	-16,800	Closed	-$1.29M	–	4026
2020 Q4	$1.29M	Hold	16,800	–	–	﹤0.01%	2862
2020 Q3	$723K	Hold	16,800	–	–	﹤0.01%	3048
2020 Q2	$726K	Hold	16,800	–	–	﹤0.01%	3139
2020 Q1	$483K	Buy	16,800 +1,700	+11%	+$68.6K	﹤0.01%	3231
2019 Q4	$958K	Buy	15,100 +6,800	+82%	+$337K	﹤0.01%	3021
2019 Q3	$234K	Hold	8,300	–	–	﹤0.01%	3569
2019 Q2	$220K	Buy	+8,300	New	+$182K	﹤0.01%	3432

Other funds holding ARWR

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Norges Bank Oslo, Norway $1T AUM

Invesco Atlanta, Georgia $1.26T AUM 61.52% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

FAM

Fred Alger Management New York $30B AUM 76.99% 1-Year Est. Return

David Shaw's ARWR Position: Q2 2026 in Review

David Shaw reduced its Arrowhead Research (ARWR) stake by 64% in Q2 2026, selling an estimated $55.6M and leaving 431,560 shares worth $35.2M. The position accounts for 0.02% of the portfolio, ranked #954.

David Shaw first reported a position in ARWR in Q1 2014 and has held it in 37 quarters since. The position peaked at $74.2M in Q1 2026. 498 funds tracked by Wall St. Rank hold ARWR as of Q2 2026.

David Shaw held 431,560 shares of Arrowhead Research worth $35.2M as of Q2 2026.
David Shaw sold 752,278 Arrowhead Research shares in Q2 2026, an estimated $55.6M.
Arrowhead Research made up 0.02% of David Shaw's portfolio in Q2 2026, its #954 holding.
David Shaw first reported a position in Arrowhead Research in Q1 2014 and has held it in 37 quarters since.
David Shaw's Arrowhead Research position peaked at $74.2M in Q1 2026.
498 funds tracked by Wall St. Rank held Arrowhead Research as of Q2 2026.

Based on D.E. Shaw & Co's 13F filing for Q2 2026, filed 14 Aug 2026.