D.E. Shaw & Co’s Arrowhead Research ARWR Stock Holding History

D.E. Shaw & Co’s Portfolio ARWR Stock Details ARWR Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q3	–	Sell	-58,500	Closed	-$924K	–	4547
2025 Q2	$924K	Buy	58,500 +36,900	+171%	+$529K	﹤0.01%	3291
2025 Q1	$275K	Buy	+21,600	New	+$393K	﹤0.01%	3800
2024 Q4	–	Sell	-11,100	Closed	-$215K	–	4397
2024 Q3	$215K	Buy	+11,100	New	+$271K	﹤0.01%	4121
2022 Q1	–	Sell	-10,000	Closed	-$663K	–	5510
2021 Q4	$663K	Hold	10,000	–	–	﹤0.01%	4230
2021 Q3	$624K	Hold	10,000	–	–	﹤0.01%	3943
2021 Q2	$828K	Hold	10,000	–	–	﹤0.01%	3695
2021 Q1	$663K	Hold	10,000	–	–	﹤0.01%	3371
2020 Q4	$767K	Hold	10,000	–	–	﹤0.01%	3188
2020 Q3	$431K	Sell	10,000 -24,900	-71%	-$1.07M	﹤0.01%	3295
2020 Q2	$1.51M	Buy	34,900 +14,900	+75%	+$526K	﹤0.01%	2628
2020 Q1	$575K	Hold	20,000	–	–	﹤0.01%	3137
2019 Q4	$1.27M	Buy	+20,000	New	+$992K	﹤0.01%	2810
2014 Q2	–	Sell	-33,500	Closed	-$550K	–	4167
2014 Q1	$550K	Buy	+33,500	New	+$588K	﹤0.01%	3517

Other funds holding ARWR

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Norges Bank Oslo, Norway $1T AUM

Invesco Atlanta, Georgia $1.26T AUM 61.52% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

FAM

Fred Alger Management New York $30B AUM 76.99% 1-Year Est. Return

D.E. Shaw & Co's ARWR Position: Q2 2026 in Review

D.E. Shaw & Co reduced its Arrowhead Research (ARWR) stake by 64% in Q2 2026, selling an estimated $55.6M and leaving 431,560 shares worth $35.2M. The position accounts for 0.02% of the portfolio, ranked #954.

D.E. Shaw & Co first reported a position in ARWR in Q1 2014 and has held it in 37 quarters since. The position peaked at $74.2M in Q1 2026. 501 funds tracked by Wall St. Rank hold ARWR as of Q2 2026.

D.E. Shaw & Co held 431,560 shares of Arrowhead Research worth $35.2M as of Q2 2026.
D.E. Shaw & Co sold 752,278 Arrowhead Research shares in Q2 2026, an estimated $55.6M.
Arrowhead Research made up 0.02% of D.E. Shaw & Co's portfolio in Q2 2026, its #954 holding.
D.E. Shaw & Co first reported a position in Arrowhead Research in Q1 2014 and has held it in 37 quarters since.
D.E. Shaw & Co's Arrowhead Research position peaked at $74.2M in Q1 2026.
501 funds tracked by Wall St. Rank held Arrowhead Research as of Q2 2026.

Based on D.E. Shaw & Co's 13F filing for Q2 2026, filed 14 Aug 2026.