D.E. Shaw & Co’s Arrowhead Research ARWR Stock Holding History

D.E. Shaw & Co’s Portfolio ARWR Stock Details ARWR Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$564K	Sell	9,000 -9,000	-50%	-$570K	﹤0.01%	3786
2025 Q4	$1.2M	Buy	+18,000	New	+$882K	﹤0.01%	3423
2025 Q3	–	Sell	-47,300	Closed	-$747K	–	4546
2025 Q2	$747K	Buy	+47,300	New	+$679K	﹤0.01%	3431
2021 Q1	–	Sell	-16,800	Closed	-$1.29M	–	4026
2020 Q4	$1.29M	Hold	16,800	–	–	﹤0.01%	2862
2020 Q3	$723K	Hold	16,800	–	–	﹤0.01%	3048
2020 Q2	$726K	Hold	16,800	–	–	﹤0.01%	3139
2020 Q1	$483K	Buy	16,800 +1,700	+11%	+$68.6K	﹤0.01%	3231
2019 Q4	$958K	Buy	15,100 +6,800	+82%	+$337K	﹤0.01%	3021
2019 Q3	$234K	Hold	8,300	–	–	﹤0.01%	3569
2019 Q2	$220K	Buy	+8,300	New	+$182K	﹤0.01%	3432

Other funds holding ARWR

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

VPM

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

FAM

Fred Alger Management New York $22.8B AUM 64.63% 1-Year Est. Return

Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return

VPC

Vestal Point Capital New York $3.58B AUM 189.12% 1-Year Est. Return

D.E. Shaw & Co's ARWR Position: Q1 2026 in Review

D.E. Shaw & Co increased its Arrowhead Research (ARWR) stake by 710% in Q1 2026, buying an estimated $65.7M and bringing the position to 1,183,838 shares worth $74.2M. The position accounts for 0.04% of the portfolio, ranked #497.

D.E. Shaw & Co first reported a position in ARWR in Q1 2014 and has held it in 36 quarters since. 436 funds tracked by Wall St. Rank hold ARWR as of Q1 2026.

D.E. Shaw & Co held 1,183,838 shares of Arrowhead Research worth $74.2M as of Q1 2026.
D.E. Shaw & Co bought 1,037,774 Arrowhead Research shares in Q1 2026, an estimated $65.7M.
Arrowhead Research made up 0.04% of D.E. Shaw & Co's portfolio in Q1 2026, its #497 holding.
D.E. Shaw & Co first reported a position in Arrowhead Research in Q1 2014 and has held it in 36 quarters since.
436 funds tracked by Wall St. Rank held Arrowhead Research as of Q1 2026.

Based on D.E. Shaw & Co's 13F filing for Q1 2026, filed 15 May 2026.