Ameriprise
UPB

Ameriprise’s Upstream Bio Inc UPB Stock Holding History

Ameriprise’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-56,557
Closed -$1.54M – 4247
2025
Q4 		$1.54M Buy
+56,557
New +$1.41M ﹤0.01% 3134

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
YIH
Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

Ameriprise's UPB Position: Q1 2026 in Review

Ameriprise sold out of Upstream Bio Inc (UPB) in Q1 2026, closing a stake of 56,557 shares — an estimated $1.54M sold.

Ameriprise first reported a position in UPB in Q4 2025 and held it in 1 quarter. The position peaked at $1.54M in Q4 2025. 140 funds tracked by Wall St. Rank hold UPB as of Q1 2026.

  • Ameriprise reported no remaining Upstream Bio Inc position as of Q1 2026 after selling out during the quarter.
  • Ameriprise sold 56,557 Upstream Bio Inc shares in Q1 2026, an estimated $1.54M.
  • Ameriprise first reported a position in Upstream Bio Inc in Q4 2025 and held it in 1 quarter.
  • Ameriprise's Upstream Bio Inc position peaked at $1.54M in Q4 2025.
  • 140 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q1 2026.

Based on Ameriprise's 13F filing for Q1 2026, filed 15 May 2026.