5VM
SLN

5AM Venture Management’s Silence Therapeutics SLN Stock Holding History

5AM Venture Management’s Portfolio SLN Stock Details SLN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$2.51M Hold
476,200
– – 0.7% 20
2025
Q4 		$2.9M Hold
476,200
– – 0.91% 20
2025
Q3 		$2.47M Hold
476,200
– – 0.91% 21
2025
Q2 		$2.76M Hold
476,200
– – 1.06% 23
2025
Q1 		$1.34M Hold
476,200
– – 0.51% 27
2024
Q4 		$3.28M Hold
476,200
– – 0.78% 26
2024
Q3 		$8.66M Hold
476,200
– – 1.79% 18
2024
Q2 		$9.05M Hold
476,200
– – 2.02% 16
2024
Q1 		$10.3M Buy
+476,200
New +$10.4M 2.3% 16

Other funds holding SLN

TCM
TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return
RG
Redmile Group San Francisco, California $1.51B AUM 164.17% 1-Year Est. Return
NCM
Nantahala Capital Management New Canaan, Connecticut $2.72B AUM 121.58% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
GPP
Great Point Partners Greenwich, Connecticut $435M AUM 318.81% 1-Year Est. Return
NI
Nextech Invest Zurich, Switzerland $1.42B AUM 304.47% 1-Year Est. Return
TAM
TFG Asset Management Grand Cayman, Cayman Islands $515M AUM 24.47% 1-Year Est. Return
IC
Ikarian Capital Dallas, Texas $1.23B AUM 600.17% 1-Year Est. Return

5AM Venture Management's SLN Position: Q1 2026 in Review

5AM Venture Management held its Silence Therapeutics (SLN) position steady in Q1 2026 at 476,200 shares worth $2.51M. The position accounts for 0.7% of the portfolio, ranked #20.

5AM Venture Management first reported a position in SLN in Q1 2024 and has held it in 9 quarters since. The position peaked at $10.3M in Q1 2024. 56 funds tracked by Wall St. Rank hold SLN as of Q1 2026.

  • 5AM Venture Management held 476,200 shares of Silence Therapeutics worth $2.51M as of Q1 2026.
  • 5AM Venture Management left its Silence Therapeutics share count unchanged in Q1 2026.
  • Silence Therapeutics made up 0.7% of 5AM Venture Management's portfolio in Q1 2026, its #20 holding.
  • 5AM Venture Management first reported a position in Silence Therapeutics in Q1 2024 and has held it in 9 quarters since.
  • 5AM Venture Management's Silence Therapeutics position peaked at $10.3M in Q1 2024.
  • 56 funds tracked by Wall St. Rank held Silence Therapeutics as of Q1 2026.

Based on 5AM Venture Management's 13F filing for Q1 2026, filed 15 May 2026.