5AM Venture Management’s Silence Therapeutics SLN Stock Holding History

5AM Venture Management’s Portfolio SLN Stock Details SLN Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$5.23M	Hold	476,200	–	–	1.82%	16
2026 Q1	$2.51M	Hold	476,200	–	–	0.7%	20
2025 Q4	$2.9M	Hold	476,200	–	–	0.91%	20
2025 Q3	$2.47M	Hold	476,200	–	–	0.91%	21
2025 Q2	$2.76M	Hold	476,200	–	–	1.06%	23
2025 Q1	$1.34M	Hold	476,200	–	–	0.51%	27
2024 Q4	$3.28M	Hold	476,200	–	–	0.78%	26
2024 Q3	$8.66M	Hold	476,200	–	–	1.79%	18
2024 Q2	$9.05M	Hold	476,200	–	–	2.02%	16
2024 Q1	$10.3M	Buy	+476,200	New	+$10.4M	2.3%	16

Other funds holding SLN

Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return

TCM

TCG Crossover Management Palo Alto, California $4.16B AUM 983.43% 1-Year Est. Return

Redmile Group San Francisco, California $1.49B AUM 208.7% 1-Year Est. Return

NCM

Nantahala Capital Management New Canaan, Connecticut $3.01B AUM 119.46% 1-Year Est. Return

Citadel Advisors Miami, Florida $875B AUM 40.89% 1-Year Est. Return

Nextech Invest Zurich, Switzerland $2.11B AUM 413.84% 1-Year Est. Return

Millennium Management New York $276B AUM 44.8% 1-Year Est. Return

TAM

TFG Asset Management Grand Cayman, Cayman Islands $635M AUM 28.07% 1-Year Est. Return

SCM

Soleus Capital Management Greenwich, Connecticut $2.9B AUM 169.69% 1-Year Est. Return

Balyasny Asset Management Chicago, Illinois $80.2B AUM 51.53% 1-Year Est. Return

5AM Venture Management's SLN Position: Q2 2026 in Review

5AM Venture Management held its Silence Therapeutics (SLN) position steady in Q2 2026 at 476,200 shares worth $5.23M. The position accounts for 1.82% of the portfolio, ranked #16.

5AM Venture Management first reported a position in SLN in Q1 2024 and has held it in 10 quarters since. The position peaked at $10.3M in Q1 2024. 72 funds tracked by Wall St. Rank hold SLN as of Q2 2026.

5AM Venture Management held 476,200 shares of Silence Therapeutics worth $5.23M as of Q2 2026.
5AM Venture Management left its Silence Therapeutics share count unchanged in Q2 2026.
Silence Therapeutics made up 1.82% of 5AM Venture Management's portfolio in Q2 2026, its #16 holding.
5AM Venture Management first reported a position in Silence Therapeutics in Q1 2024 and has held it in 10 quarters since.
5AM Venture Management's Silence Therapeutics position peaked at $10.3M in Q1 2024.
72 funds tracked by Wall St. Rank held Silence Therapeutics as of Q2 2026.

Based on 5AM Venture Management's 13F filing for Q2 2026, filed 14 Aug 2026.