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SLN

Silence Therapeutics

65 hedge funds and large institutions have $168M invested in Silence Therapeutics in 2024 Q4 according to their latest regulatory filings, with 16 funds opening new positions, 24 increasing their positions, 13 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

85% more repeat investments, than reductions

Existing positions increased: 24 | Existing positions reduced: 13

2.41% less ownership

Funds ownership: 20.14%17.73% (-2.4%)

6% less funds holding

Funds holding: 6965 (-4)

20% less first-time investments, than exits

New positions opened: 16 | Existing positions closed: 20

40% less funds holding in top 10

Funds holding in top 10: 53 (-2)

66% less capital invested

Capital invested by funds: $493M → $168M (-$325M)

93% less call options, than puts

Call options by funds: $3K | Put options by funds: $45K

Holders
65
Holders Change
-4
Holders Change %
-5.8%
% of All Funds
0.86%
Holding in Top 10
3
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-40%
% of All Funds
0.04%
New
16
Increased
24
Reduced
13
Closed
20
Calls
$3K
Puts
$45K
Net Calls
-$42K
Net Calls Change
-$14K
Name Holding Trade Value Shares
Change
Change in
Stake
TCM
1
TCG Crossover Management
California
$20.9M
SL
2
Siren LLC
Connecticut
$19.5M
RG
3
Redmile Group
California
$16.5M +$6.45M +500,000 +26%
Morgan Stanley
4
Morgan Stanley
New York
$11.4M +$12.2M +941,651 +131%
LOAMU
5
Lombard Odier Asset Management (USA)
New York
$10.2M -$10.4M -808,054 -30%
FLSM
6
Frazier Life Sciences Management
California
$7.9M
VC
7
Vivo Capital
California
$7.61M
NCM
8
Nantahala Capital Management
Connecticut
$7.22M +$11M +849,676 +425%
NI
9
Nextech Invest
Switzerland
$6.55M
EAM
10
Eventide Asset Management
Massachusetts
$4.4M
Point72 Asset Management
11
Point72 Asset Management
Connecticut
$4.36M +$2.13M +165,300 +35%
CF
12
Cantor Fitzgerald
New York
$3.71M +$2.65M +205,534 +62%
Bank of America
13
Bank of America
North Carolina
$3.43M +$6.43M +498,032 +48,166%
WP
14
Woodline Partners
California
$3.43M +$1.18M +91,829 +23%
PHP
15
Parkman Healthcare Partners
Connecticut
$3.38M -$87.6K -6,790 -1%
Marshall Wace
16
Marshall Wace
United Kingdom
$3.36M +$4.14M +320,472 +190%
5VM
17
5AM Venture Management
California
$3.28M
Millennium Management
18
Millennium Management
New York
$3.26M -$8.22M -636,678 -57%
SVCM
19
Saturn V Capital Management
Texas
$2.72M -$1.11M -86,103 -18%
ACM
20
Aquilo Capital Management
California
$2.53M +$645K +50,000 +16%
UBS Group
21
UBS Group
Switzerland
$2.45M +$3.68M +285,410 +404%
BFM
22
Boothbay Fund Management
New York
$2.42M +$2.33M +180,372 +105%
SG Americas Securities
23
SG Americas Securities
New York
$2.19M -$330K -25,562 -7%
Citadel Advisors
24
Citadel Advisors
Florida
$1.95M -$1.99M -153,960 -35%
BlackRock
25
BlackRock
New York
$1.46M +$2.73M +211,507 New

SLN Hedge Fund Activity: Q4 2024 in Review

65 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Silence Therapeutics (SLN) for Q4 2024, worth a combined $168M — down 66% from $493M a quarter earlier.

Sellers outnumbered buyers: 20 funds closed out of SLN and 16 opened new positions — a net loss of 4 holders — while 13 trimmed existing stakes and 24 added.

The largest buyer was Morgan Stanley, adding an estimated $12.2M. The largest seller was Janus Henderson Group, exiting entirely with an estimated $19.8M sold.

  • 65 institutional investors held Silence Therapeutics (SLN) as of Q4 2024, down from 69 in Q3 2024.
  • Funds reported $168M of Silence Therapeutics stock for Q4 2024, down 66% quarter-over-quarter.
  • 16 funds opened new Silence Therapeutics positions in Q4 2024 and 20 closed out, a net change of -4 holders.
  • The largest Silence Therapeutics buyer in Q4 2024 was Morgan Stanley, an estimated $12.2M added.
  • The largest Silence Therapeutics seller in Q4 2024 was Janus Henderson Group, an estimated $19.8M sold.

Based on aggregated 13F filings for Q4 2024.