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SLN

Silence Therapeutics

59 hedge funds and large institutions have $60.6M invested in Silence Therapeutics in 2025 Q1 according to their latest regulatory filings, with 5 funds opening new positions, 18 increasing their positions, 25 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

2.26% less ownership

Funds ownership: 17.73%15.47% (-2.3%)

9% less funds holding

Funds holding: 6559 (-6)

28% less repeat investments, than reductions

Existing positions increased: 18 | Existing positions reduced: 25

43% less call options, than puts

Call options by funds: $4K | Put options by funds: $7K

55% less first-time investments, than exits

New positions opened: 5 | Existing positions closed: 11

64% less capital invested

Capital invested by funds: $168M → $60.6M (-$108M)

100% less funds holding in top 10

Funds holding in top 10: 30 (-3)

Holders
59
Holders Change
-6
Holders Change %
-9.23%
% of All Funds
0.79%
Holding in Top 10
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-100%
% of All Funds
New
5
Increased
18
Reduced
25
Closed
11
Calls
$4K
Puts
$7K
Net Calls
-$3K
Net Calls Change
+$39K
Name Holding Trade Value Shares
Change
Change in
Stake
TCM
1
TCG Crossover Management
California
$8.55M
SL
2
Siren LLC
Connecticut
$7.87M -$205K -41,937 -1%
RG
3
Redmile Group
California
$6.25M -$900K -184,370 -8%
Morgan Stanley
4
Morgan Stanley
New York
$5.64M +$1.65M +337,037 +20%
LOAMU
5
Lombard Odier Asset Management (USA)
New York
$4.04M -$30.7K -6,289 -0.3%
FLSM
6
Frazier Life Sciences Management
California
$3.24M
VC
7
Vivo Capital
California
$3.12M
NCM
8
Nantahala Capital Management
Connecticut
$2.94M -$35.4K -7,249 -0.7%
NI
9
Nextech Invest
Switzerland
$2.69M
CF
10
Cantor Fitzgerald
New York
$2.18M +$1.14M +234,119 +43%
SVCM
11
Saturn V Capital Management
Texas
$2.07M +$1.65M +337,439 +85%
5VM
12
5AM Venture Management
California
$1.34M
PHP
13
Parkman Healthcare Partners
Connecticut
$1.13M -$436K -89,334 -18%
Millennium Management
14
Millennium Management
New York
$1.12M -$374K -76,690 -16%
UBS Group
15
UBS Group
Switzerland
$901K -$179K -36,557 -10%
SG Americas Securities
16
SG Americas Securities
New York
$869K -$45.6K -9,339 -3%
BFM
17
Boothbay Fund Management
New York
$705K -$496K -101,515 -29%
Marshall Wace
18
Marshall Wace
United Kingdom
$644K -$1.27M -260,471 -53%
MCM
19
M28 Capital Management
Connecticut
$522K
BlackRock
20
BlackRock
New York
$509K -$152K -31,072 -15%
HSBC Holdings
21
HSBC Holdings
United Kingdom
$499K
Bank of Montreal
22
Bank of Montreal
Ontario, Canada
$447K +$457K +93,586 +144%
SSA
23
Schonfeld Strategic Advisors
New York
$423K +$131K +26,796 +22%
Walleye Capital
24
Walleye Capital
New York
$384K +$487K +99,753 +274%
WP
25
Woodline Partners
California
$379K -$1.78M -364,240 -73%

SLN Hedge Fund Activity: Q1 2025 in Review

59 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Silence Therapeutics (SLN) for Q1 2025, worth a combined $60.6M — down 64% from $168M a quarter earlier.

Sellers outnumbered buyers: 11 funds closed out of SLN and 5 opened new positions — a net loss of 6 holders — while 25 trimmed existing stakes and 18 added.

The largest buyer was Saturn V Capital Management, adding an estimated $1.65M. The largest seller was Eventide Asset Management, exiting entirely with an estimated $4.4M sold.

  • 59 institutional investors held Silence Therapeutics (SLN) as of Q1 2025, down from 65 in Q4 2024.
  • Funds reported $60.6M of Silence Therapeutics stock for Q1 2025, down 64% quarter-over-quarter.
  • 5 funds opened new Silence Therapeutics positions in Q1 2025 and 11 closed out, a net change of -6 holders.
  • The largest Silence Therapeutics buyer in Q1 2025 was Saturn V Capital Management, an estimated $1.65M added.
  • The largest Silence Therapeutics seller in Q1 2025 was Eventide Asset Management, an estimated $4.4M sold.

Based on aggregated 13F filings for Q1 2025.