SLN

Silence Therapeutics
SLN

Overview Fund Activity

55 hedge funds and large institutions have $108M invested in Silence Therapeutics in 2025 Q2 according to their latest regulatory filings, with 8 funds opening new positions, 13 increasing their positions, 19 reducing their positions, and 13 closing their positions.

Holders
55
Holders Change
-5
Holders Change %
-8.33%
% of All Funds
0.74%
Holding in Top 10
2
Holding in Top 10 Change
+2
Holding in Top 10 Change %
%
% of All Funds
0.03%
New
8
Increased
13
Reduced
19
Closed
13
Calls
$132K
Puts
$7K
Net Calls
+$125K
Net Calls Change
+$128K

Top Buyers

1
IC
1
Ikarian Capital
Texas
$1.4M
2
SL
2
Siren LLC
Connecticut
$16.9M
3
Jane Street
3
Jane Street
New York
$219K
4
WC
4
Wexford Capital
Florida
$157K
5
MCM
5
Massar Capital Management
Connecticut
$115K

Top Sellers

1
Morgan Stanley
1
Morgan Stanley
New York
$7.03M
2
SVCM
2
Saturn V Capital Management
Texas
$201K
3
Millennium Management
3
Millennium Management
New York
$1.15M
4
PHP
4
Parkman Healthcare Partners
Connecticut
$0
5
FLSM
5
Frazier Life Sciences Management
California
$5.63M
Name Market Value Shares Shares
Change 		Shares
Change %
TCM
1
TCG Crossover Management
California
$17.6M 3,033,560 – –
SL
2
Siren LLC
Connecticut
$16.9M 2,911,438 +121,605 +4%
RG
3
Redmile Group
California
$12.6M 2,164,777 -50,170 -2%
LOAMU
4
Lombard Odier Asset Management (USA)
New York
$7.81M 1,849,734 – –
Morgan Stanley
5
Morgan Stanley
New York
$7.03M 1,211,758 -788,347 -39%
VC
6
Vivo Capital
California
$6.41M 1,105,454 – –
NCM
7
Nantahala Capital Management
Connecticut
$6.05M 1,042,427 – –
FLSM
8
Frazier Life Sciences Management
California
$5.63M 970,130 -178,461 -16%
NI
9
Nextech Invest
Switzerland
$5.52M 952,400 – –
CF
10
Cantor Fitzgerald
New York
$4.58M 789,039 +15,194 +2%
5VM
11
5AM Venture Management
California
$2.76M 476,200 – –
SG Americas Securities
12
SG Americas Securities
New York
$1.79M 308,331 +42 +0%
BFM
13
Boothbay Fund Management
New York
$1.46M 252,421 +2,409 +1%
IC
14
Ikarian Capital
Texas
$1.4M 873,568 +873,568 New
UBS Group
15
UBS Group
Switzerland
$1.33M 228,509 -91,005 -28%
Millennium Management
16
Millennium Management
New York
$1.15M 198,647 -198,215 -50%
MCM
17
M28 Capital Management
Connecticut
$1.07M 185,100 – –
HSBC Holdings
18
HSBC Holdings
United Kingdom
$1.02M 172,834 – –
Marshall Wace
19
Marshall Wace
United Kingdom
$1.02M 175,862 -52,556 -23%
BlackRock
20
BlackRock
New York
$976K 168,235 -12,200 -7%
Bank of Montreal
21
Bank of Montreal
Ontario, Canada
$846K 145,812 -12,781 -8%
WP
22
Woodline Partners
California
$362K 62,459 -72,033 -54%
Two Sigma Investments
23
Two Sigma Investments
New York
$344K 59,312 -16,696 -22%
Osaic Holdings
24
Osaic Holdings
Arizona
$281K 40,867 -30,630 -43%
Two Sigma Advisers
25
Two Sigma Advisers
New York
$230K 39,600 -9,600 -20%
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