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Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
SMMT icon
26
Summit Therapeutics
SMMT
$10.4B
$10.4B $13.02 3.12%
APGE icon
27
Apogee Therapeutics
APGE
$10.1B
$10.1B $134.09 0.16%
KRYS icon
28
Krystal Biotech
KRYS
$10.1B
$10.1B $341.12 7.01%
HALO icon
29
Halozyme
HALO
$9.79B
$9.79B $82.54 0.91%
CRNX icon
30
Crinetics Pharmaceuticals
CRNX
$8.84B
$8.84B $83.52 0.13%
PTGX icon
31
Protagonist Therapeutics
PTGX
$8.79B
$8.79B $136.64 1.44%
IONS icon
32
Ionis Pharmaceuticals
IONS
$8.6B
$8.6B $51.77 2.83%
PRAX icon
33
Praxis Precision Medicines
PRAX
$8.58B
$8.58B $307.83 0.03%
SYRE icon
34
Spyre Therapeutics
SYRE
$8.54B
$8.54B $98.33 3.12%
KYMR icon
35
Kymera Therapeutics
KYMR
$8.51B
$8.51B $103.40 3.37%
TGTX icon
36
TG Therapeutics
TGTX
$7.96B
$7.96B $52.03 2.8%
IMVT icon
37
Immunovant
IMVT
$7.93B
$7.93B $38.62 2.18%
PCVX icon
38
Vaxcyte
PCVX
$7.81B
$7.81B $54.08 3.36%
IBRX icon
39
ImmunityBio
IBRX
$7.51B
$7.51B $7.17 3.76%
RYTM icon
40
Rhythm Pharmaceuticals
RYTM
$6.81B
$6.81B $99.25 6.14%
COGT icon
41
Cogent Biosciences
COGT
$6.65B
$6.65B $38.93 5.88%
MIRM icon
42
Mirum Pharmaceuticals
MIRM
$6.46B
$6.46B $105.95 5.9%
BLTE
43
Belite Bio
BLTE
$6.36B
$6.36B $158.61 0.82%
ERAS icon
44
Erasca
ERAS
$6.3B
$6.3B $18.15 2.84%
CGON icon
45
CG Oncology
CGON
$6.28B
$6.28B $71.19 2.52%
XENE icon
46
Xenon Pharmaceuticals
XENE
$6.06B
$6.06B $62.67 2.37%
DNTH icon
47
Dianthus Therapeutics
DNTH
$5.84B
$5.84B $106.92 5.08%
ORKA
48
Oruka Therapeutics
ORKA
$5.82B
$5.82B $96.51 1.38%
DFTX
49
Definium Therapeutics
DFTX
$5.78B
$5.78B $43.52 2.18%
LGND icon
50
Ligand Pharmaceuticals
LGND
$5.76B
$5.76B $287.54 2.95%
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Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 566 Biotechnology industry stocks tracked by Wall St. Rank, worth a combined $1.2T.

The largest by market cap are Vertex Pharmaceuticals (VRTX) at $121B, Regeneron Pharmaceuticals (REGN) at $78.5B and argenx (ARGX) at $53.4B.

Among institutional investors, Atrium Therapeutics (RNA) drew the most net new fund positions in Q1 2026: 162 funds opened new positions.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q1 2026.