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Vertex Pharmaceuticals

1,756 hedge funds and large institutions have $120B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 194 funds opening new positions, 706 increasing their positions, 618 reducing their positions, and 111 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 194 | Existing positions closed: 111

14% more repeat investments, than reductions

Existing positions increased: 706 | Existing positions reduced: 618

13% more capital invested

Capital invested by funds: $106B → $120B (+$13.6B)

3% more funds holding

Funds holding: 1,6971,756 (+59)

1.53% more ownership

Funds ownership: 93.6%95.13% (+1.5%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,756
Holders Change
+59
Holders Change %
+3.48%
% of All Funds
21.12%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
194
Increased
706
Reduced
618
Closed
111
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M

VRTX Hedge Fund Activity: Q2 2026 in Review

1,756 of the 8,316 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $120B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 194 funds opened new VRTX positions and 111 closed out — a net gain of 83 holders — while 706 added to existing stakes and 618 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,756 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,697 in Q1 2026.
  • Funds reported $120B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 194 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 111 closed out, a net change of +83 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.