Vertex PharmaceuticalsVRTX
About: Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
Employees: 6,100
Fund manager confidence
Based on 2025 Q1 regulatory disclosures by fund managers ($100M+ AUM)
63% more first-time investments, than exits
New positions opened: 205 | Existing positions closed: 126
63% more funds holding in top 10
Funds holding in top 10: 16 [Q4 2024] → 26 (+10) [Q1 2025]
29% more call options, than puts
Call options by funds: $771M | Put options by funds: $596M
20% more capital invested
Capital invested by funds: $95.5B [Q4 2024] → $114B (+$18.8B) [Q1 2025]
10% more repeat investments, than reductions
Existing positions increased: 625 | Existing positions reduced: 566
3% more funds holding
Funds holding: 1,534 [Q4 2024] → 1,580 (+46) [Q1 2025]
0.22% more ownership
Funds ownership: 91.6% [Q4 2024] → 91.81% (+0.22%) [Q1 2025]
Research analyst outlook
7 Wall Street Analysts provided 1 year price targets over the past 3 months
7 analyst ratings
RBC Capital Brian Abrahams | 7%downside $423 | Sector Perform Maintained | 6 May 2025 |
Scotiabank Greg Harrison | 3%downside $442 | Sector Perform Maintained | 6 May 2025 |
Morgan Stanley Matthew Harrison | 2%upside $464 | Equal-Weight Maintained | 6 May 2025 |
JP Morgan Jessica Fye | 13%upside $515 | Overweight Maintained | 6 May 2025 |
Cantor Fitzgerald Carter Gould | 17%upside $535 | Overweight Reiterated | 6 May 2025 |
Financial journalist opinion
Based on 13 articles about VRTX published over the past 30 days









