Vertex PharmaceuticalsVRTX
About: Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
Employees: 6,100
Fund manager confidence
Based on 2025 Q2 regulatory disclosures by fund managers ($100M+ AUM)
92% more call options, than puts
Call options by funds: $716M | Put options by funds: $374M
1.47% more ownership
Funds ownership: 91.96% [Q1] → 93.42% (+1.47%) [Q2]
1% less repeat investments, than reductions
Existing positions increased: 596 | Existing positions reduced: 602
4% less funds holding
Funds holding: 1,592 [Q1] → 1,521 (-71) [Q2]
7% less capital invested
Capital invested by funds: $115B [Q1] → $107B (-$7.71B) [Q2]
18% less first-time investments, than exits
New positions opened: 116 | Existing positions closed: 142
46% less funds holding in top 10
Funds holding in top 10: 26 [Q1] → 14 (-12) [Q2]
Research analyst outlook
14 Wall Street Analysts provided 1 year price targets over the past 3 months
14 analyst ratings
Canaccord Genuity Whitney Ijem | 6%upside $411 | Hold Maintained | 6 Aug 2025 |
Guggenheim Debjit Chattopadhyay | 40%upside $546 | Buy Maintained | 6 Aug 2025 |
Wells Fargo Mohit Bansal | 18%upside $460 | Overweight Upgraded | 6 Aug 2025 |
Truist Securities Joon Lee | 26%upside $490 | Buy Maintained | 5 Aug 2025 |
Scotiabank Greg Harrison | 13%upside $438 | Sector Perform Maintained | 5 Aug 2025 |
Financial journalist opinion
Based on 42 articles about VRTX published over the past 30 days









