|
1
|
|
US$1.92億
|
+US$1578萬
|
+491,643
|
+9%
|
|
|
2
|
|
US$1.84億
|
–
|
–
|
–
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
US$1.74億
|
-US$226萬
|
-70,566
|
-1%
|
|
|
4
|
Lynx1 Capital Management
San Juan,
Puerto Rico
|
US$1.32億
|
-US$2328萬
|
-725,269
|
-15%
|
|
|
5
|
Redmile Group
San Francisco,
California
|
US$1.29億
|
-US$700萬
|
-218,200
|
-5%
|
|
|
6
|
Wellington Management Group
Boston,
Massachusetts
|
US$1.15億
|
+US$1359萬
|
+423,601
|
+14%
|
|
|
7
|
|
US$1.13億
|
+US$94.7萬
|
+29,515
|
+0.9%
|
|
|
8
|
Baker Bros. Advisors
New York
|
US$1.09億
|
–
|
–
|
–
|
|
|
9
|
Toronto Dominion Bank
Toronto, Ontario,
Ontario, Canada
|
US$1.04億
|
–
|
–
|
–
|
|
|
10
|
State Street
Boston,
Massachusetts
|
US$9333萬
|
+US$1848萬
|
+575,728
|
+25%
|
|
|
11
|
T. Rowe Price Associates
Baltimore,
Maryland
|
US$8709萬
|
+US$2335萬
|
+727,568
|
+38%
|
|
|
12
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
US$8464萬
|
+US$742萬
|
+231,334
|
+10%
|
|
|
13
|
BVF Inc
San Francisco,
California
|
US$8336萬
|
–
|
–
|
–
|
|
|
14
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
US$7902萬
|
+US$6946萬
|
+2,164,226
|
+863%
|
|
|
15
|
Siren LLC
Greenwich,
Connecticut
|
US$6529萬
|
–
|
–
|
–
|
|
|
16
|
Deerfield Management
New York
|
US$5966萬
|
–
|
–
|
–
|
|
|
17
|
|
US$5936萬
|
+US$5823萬
|
+1,814,408
|
新
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
US$4988萬
|
+US$648萬
|
+202,049
|
+15%
|
|
|
19
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
US$3692萬
|
+US$710萬
|
+221,373
|
+24%
|
|
|
20
|
Dimensional Fund Advisors
Austin,
Texas
|
US$3317萬
|
+US$76.9萬
|
+23,975
|
+2%
|
|
|
21
|
Polar Capital Holdings
London,
United Kingdom
|
US$2728萬
|
-US$959萬
|
-298,795
|
-26%
|
|
|
22
|
EcoR1 Capital
San Francisco,
California
|
US$2405萬
|
+US$2038萬
|
+635,000
|
+635%
|
|
|
23
|
MPM BioImpact
Boston,
Massachusetts
|
US$2367萬
|
-US$140萬
|
-43,724
|
-6%
|
|
|
24
|
Opaleye Management
Boston,
Massachusetts
|
US$2290萬
|
–
|
–
|
–
|
|
|
25
|
|
US$1883萬
|
-US$820萬
|
-255,358
|
-31%
|
|
