|
1
|
Fidelity Investments
Boston,
Massachusetts
|
US$14.2億
|
+US$5579萬
|
+649,306
|
+6%
|
|
|
2
|
Baker Bros. Advisors
New York
|
US$9.9億
|
–
|
–
|
–
|
|
|
3
|
Avoro Capital Advisors
New York
|
US$8.57億
|
–
|
–
|
–
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
US$8.16億
|
+US$9040萬
|
+1,052,133
|
+17%
|
|
|
5
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
US$7.18億
|
+US$6807萬
|
+792,264
|
+14%
|
|
|
6
|
|
US$6.35億
|
+US$4101萬
|
+477,334
|
+9%
|
|
|
7
|
BVF Inc
San Francisco,
California
|
US$4.44億
|
-US$1.4億
|
-1,630,658
|
-30%
|
|
|
8
|
Wellington Management Group
Boston,
Massachusetts
|
US$4.21億
|
-US$1844萬
|
-214,659
|
-6%
|
|
|
9
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
US$3.43億
|
+US$1015萬
|
+118,137
|
+4%
|
|
|
10
|
Siren LLC
Greenwich,
Connecticut
|
US$3.37億
|
-US$2157萬
|
-251,000
|
-8%
|
|
|
11
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
US$3.36億
|
+US$447萬
|
+52,054
|
+2%
|
|
|
12
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
US$3.27億
|
-US$1.49億
|
-1,730,467
|
-38%
|
|
|
13
|
State Street
Boston,
Massachusetts
|
US$3.14億
|
+US$2985萬
|
+347,459
|
+15%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
US$2.08億
|
+US$1469萬
|
+170,981
|
+10%
|
|
|
15
|
Capital Research Global Investors
Los Angeles,
California
|
US$1.59億
|
-US$2444萬
|
-284,394
|
-17%
|
|
|
16
|
|
US$1.36億
|
+US$2568萬
|
+298,924
|
+34%
|
|
|
17
|
UBS Group
Zurich,
Switzerland
|
US$1.16億
|
-US$138萬
|
-16,075
|
-2%
|
|
|
18
|
Driehaus Capital Management
Chicago,
Illinois
|
US$1.05億
|
-US$1068萬
|
-124,350
|
-12%
|
|
|
19
|
Merck & Co
Rahway,
New Jersey
|
US$8854萬
|
–
|
–
|
–
|
|
|
20
|
|
US$8683萬
|
+US$6506萬
|
+757,246
|
新
|
|
|
21
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
US$8593萬
|
+US$1828萬
|
+212,718
|
+40%
|
|
|
22
|
Dimensional Fund Advisors
Austin,
Texas
|
US$8542萬
|
+US$1308萬
|
+152,273
|
+26%
|
|
|
23
|
Frontier Capital Management
Boston,
Massachusetts
|
US$8496萬
|
-US$163萬
|
-18,982
|
-2%
|
|
|
24
|
|
US$8450萬
|
-US$1194萬
|
-139,006
|
-16%
|
|
|
25
|
AllianceBernstein
Nashville,
Tennessee
|
US$8175萬
|
+US$803萬
|
+93,486
|
+11%
|
|
