|
1
|
Fidelity Investments
Boston,
Massachusetts
|
US$5530萬
|
+US$1.69萬
|
+1,484
|
+0%
|
|
|
2
|
Canaan Partners IX
Menlo Park,
California
|
US$4338萬
|
-US$730萬
|
-640,374
|
-13%
|
|
|
3
|
Deerfield Management
New York
|
US$964萬
|
–
|
–
|
–
|
|
|
4
|
Tekla Capital Management
Boston,
Massachusetts
|
US$772萬
|
+US$488萬
|
+428,031
|
+130%
|
|
|
5
|
Perceptive Advisors
New York
|
US$758萬
|
–
|
–
|
–
|
|
|
6
|
Redmile Group
San Francisco,
California
|
US$750萬
|
+US$4.79萬
|
+4,200
|
+0.6%
|
|
|
7
|
BVF Inc
San Francisco,
California
|
US$619萬
|
–
|
–
|
–
|
|
|
8
|
VHCP Management II
New York
|
US$590萬
|
–
|
–
|
–
|
|
|
9
|
BlackRock Advisors
Wilmington,
Delaware
|
US$554萬
|
+US$616萬
|
+539,834
|
+21,170%
|
|
|
10
|
BlackRock Fund Advisors
San Francisco,
California
|
US$539萬
|
+US$377萬
|
+330,966
|
+169%
|
|
|
11
|
Cormorant Asset Management
Boston,
Massachusetts
|
US$380萬
|
+US$6,991
|
+613
|
+0.2%
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
US$380萬
|
+US$161萬
|
+141,466
|
+61%
|
|
|
13
|
Franklin Resources
San Mateo,
California
|
US$341萬
|
+US$38.2萬
|
+33,500
|
+11%
|
|
|
14
|
Putnam Investments
Boston,
Massachusetts
|
US$332萬
|
–
|
–
|
–
|
|
|
15
|
State Street
Boston,
Massachusetts
|
US$260萬
|
+US$186萬
|
+162,724
|
+177%
|
|
|
16
|
|
US$239萬
|
-US$99萬
|
-86,844
|
-27%
|
|
|
17
|
Private Advisor Group
Morristown,
New Jersey
|
US$223萬
|
+US$251萬
|
+219,689
|
新
|
|
|
18
|
BlackRock Institutional Trust
San Francisco,
California
|
US$169萬
|
+US$123萬
|
+107,706
|
+186%
|
|
|
19
|
Opaleye Management
Boston,
Massachusetts
|
US$163萬
|
+US$182萬
|
+160,000
|
新
|
|
|
20
|
Eventide Asset Management
Boston,
Massachusetts
|
US$153萬
|
–
|
–
|
–
|
|
|
21
|
Montecito Bank & Trust
Santa Barbara,
California
|
US$150萬
|
+US$167萬
|
+146,544
|
新
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
US$102萬
|
+US$29.7萬
|
+26,055
|
+35%
|
|
|
23
|
BlackRock Investment Management
Wilmington,
Delaware
|
US$78.4萬
|
+US$56.2萬
|
+49,279
|
+180%
|
|
|
24
|
Geode Capital Management
Boston,
Massachusetts
|
US$77.7萬
|
+US$8.96萬
|
+7,860
|
+12%
|
|
|
25
|
Bank of New York Mellon
New York
|
US$73.3萬
|
+US$55.3萬
|
+48,474
|
+208%
|
|
