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Wave Life Sciences

189 hedge funds and large institutions have $1.05B invested in Wave Life Sciences in 2025 Q3 according to their latest regulatory filings, with 32 funds opening new positions, 61 increasing their positions, 62 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

101% more call options, than puts

Call options by funds: $9.64M | Put options by funds: $4.79M

78% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 18

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

16% more capital invested

Capital invested by funds: $903M → $1.05B (+$148M)

7% more funds holding

Funds holding: 176189 (+13)

0.97% more ownership

Funds ownership: 89.31%90.29% (+0.97%)

2% less repeat investments, than reductions

Existing positions increased: 61 | Existing positions reduced: 62

Holders
189
Holders Change
+13
Holders Change %
+7.39%
% of All Funds
2.48%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
32
Increased
61
Reduced
62
Closed
18
Calls
$9.64M
Puts
$4.79M
Net Calls
+$4.85M
Net Calls Change
+$1.79M
Name Holding Trade Value Shares
Change
Change in
Stake
Artisan Partners
26
Artisan Partners
Wisconsin
$9.03M -$8.35M -1,031,909 -46%
PCH
27
Polar Capital Holdings
United Kingdom
$7.78M +$476K +58,776 +6%
Northern Trust
28
Northern Trust
Illinois
$7.41M +$24K +2,968 +0.3%
Charles Schwab
29
Charles Schwab
California
$7.31M -$99.4K -12,286 -1%
RI
30
RTW Investments
New York
$6.59M
JP Morgan Chase
31
JP Morgan Chase
New York
$6.3M -$5.74M -708,874 -45%
Walleye Capital
32
Walleye Capital
New York
$5.35M +$2.13M +262,752 +56%
UBS Group
33
UBS Group
Switzerland
$5.17M +$796K +98,336 +16%
Bank of America
34
Bank of America
North Carolina
$4.87M +$158K +19,590 +3%
Point72 Asset Management
35
Point72 Asset Management
Connecticut
$4.86M +$5.37M +663,967 New
Jane Street
36
Jane Street
New York
$4.54M +$5.01M +619,641 New
Two Sigma Investments
37
Two Sigma Investments
New York
$4.12M +$2.59M +319,837 +132%
Schroder Investment Management Group
38
Schroder Investment Management Group
United Kingdom
$3.96M -$533K -65,834 -11%
KCM
39
Kennedy Capital Management
Missouri
$3.96M +$4.1M +506,437 +1,490%
Morgan Stanley
40
Morgan Stanley
New York
$3.71M -$8.39M -1,036,748 -67%
Wellington Management Group
41
Wellington Management Group
Massachusetts
$3.14M +$1.07M +131,732 +44%
Millennium Management
42
Millennium Management
New York
$2.86M -$2.44M -301,666 -44%
Universal-Beteiligungs- und Servicegesellschaft
43
Universal-Beteiligungs- und Servicegesellschaft
Germany
$2.7M +$83.1K +10,276 +3%
MAP
44
Moody Aldrich Partners
Massachusetts
$2.57M -$577K -71,304 -17%
BBA
45
Baker Bros. Advisors
New York
$2.52M
FMI
46
F/M Investments
District of Columbia
$2.33M +$602K +74,410 +31%
Ensign Peak Advisors
47
Ensign Peak Advisors
Utah
$2.29M
SPS
48
Susquehanna Portfolio Strategies
Pennsylvania
$2.24M +$164K +20,288 +7%
NM
49
Newtyn Management
New York
$2.2M -$809K -100,000 -25%
Bank of New York Mellon
50
Bank of New York Mellon
New York
$2.18M +$69.4K +8,574 +3%

WVE Hedge Fund Activity: Q3 2025 in Review

189 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Wave Life Sciences (WVE) for Q3 2025, worth a combined $1.05B — up 16% from $903M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new WVE positions and 18 closed out — a net gain of 14 holders — while 61 added to existing stakes and 62 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $36.5M. The largest seller was T. Rowe Price Associates, cutting an estimated $9.27M.

  • 189 institutional investors held Wave Life Sciences (WVE) as of Q3 2025, up from 176 in Q2 2025.
  • Funds reported $1.05B of Wave Life Sciences stock for Q3 2025, up 16% quarter-over-quarter.
  • 32 funds opened new Wave Life Sciences positions in Q3 2025 and 18 closed out, a net change of +14 holders.
  • The largest Wave Life Sciences buyer in Q3 2025 was Fidelity Investments, an estimated $36.5M added.
  • The largest Wave Life Sciences seller in Q3 2025 was T. Rowe Price Associates, an estimated $9.27M sold.

Based on aggregated 13F filings for Q3 2025.