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Vertex Pharmaceuticals
VRTX

Overview Fund Activity

1,536 hedge funds and large institutions have $107B invested in Vertex Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 117 funds opening new positions, 606 increasing their positions, 605 reducing their positions, and 144 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,536
Holders Change
-59
Holders Change %
-3.7%
% of All Funds
20.59%
Holding in Top 10
16
Holding in Top 10 Change
-10
Holding in Top 10 Change %
-38.46%
% of All Funds
0.21%
New
117
Increased
606
Reduced
605
Closed
144
Calls
$930M
Puts
$554M
Net Calls
+$376M
Net Calls Change
+$202M

Top Buyers

1
Capital International Investors
Capital International Investors
California
+$884M
2
Victory Capital Management
Victory Capital Management
Texas
+$836M
3
Capital Research Global Investors
Capital Research Global Investors
California
+$700M
4
Jennison Associates
Jennison Associates
New York
+$485M
5
UBS AM
UBS AM
Illinois
+$226M

Top Sellers

1
Amundi
Amundi
France
-$898M
2
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
-$840M
3
Fidelity Investments
Fidelity Investments
Massachusetts
-$588M
4
Massachusetts Financial Services
Massachusetts Financial Services
Massachusetts
-$330M
5
Wellington Management Group
Wellington Management Group
Massachusetts
-$286M
Name Holding Trade Value Shares
Change 		Shares
Change %
NIM
176
NEOS Investment Management
Connecticut
$33.9M +$11.1M +24,915 +49%
PNC Financial Services Group
177
PNC Financial Services Group
Pennsylvania
$33.9M -$893K -2,005 -3%
Daiwa Securities Group
178
Daiwa Securities Group
Japan
$33.8M +$2.05M +4,600 +6%
Rafferty Asset Management
179
Rafferty Asset Management
New York
$33.4M +$1.9M +4,278 +6%
ASRS
180
Arizona State Retirement System
Arizona
$33.4M -$197K -443 -0.6%
EAM
181
Erste Asset Management
Austria
$32.6M +$2.27M +5,133 +7%
SOMRS
182
State of Michigan Retirement System
Michigan
$32.3M +$178K +400 +0.6%
Janney Montgomery Scott
183
Janney Montgomery Scott
Pennsylvania
$32M +$1.46M +3,271 +5%
Vontobel Holding
184
Vontobel Holding
Switzerland
$32M -$1.34M -3,008 -4%
CLGM
185
Capitolis Liquid Global Markets
New York
$31.6M +$31.6M +71,000 New
BS
186
Banco Santander
Spain
$31.2M +$2.74M +6,160 +10%
TRSOTSOK
187
Teachers Retirement System of the State of Kentucky
Kentucky
$30.4M +$2.31M +5,185 +8%
GIA
188
Gateway Investment Advisers
Ohio
$29.3M -$26.3K -59 -0.1%
NAM
189
Nissay Asset Management
Japan
$29.2M +$814K +1,828 +3%
Nisa Investment Advisors
190
Nisa Investment Advisors
Missouri
$29.1M -$1.28M -2,883 -4%
Alyeska Investment Group
191
Alyeska Investment Group
Illinois
$28.9M -$163M -366,804 -85%
ATN
192
AMF Tjänstepension
Sweden
$28.8M +$1.65M +3,710 +6%
Comerica Bank
193
Comerica Bank
Texas
$28.8M -$332K -746 -1%
Caisse de Depot et Placement du Quebec (CDPQ)
194
Caisse de Depot et Placement du Quebec (CDPQ)
Quebec, Canada
$28.7M -$26.9M -60,451 -48%
DIA
195
Davidson Investment Advisors
Montana
$28.4M +$359K +806 +1%
COPPSERS
196
Commonwealth of Pennsylvania Public School Employees Retirement System
Pennsylvania
$28M +$1.89M +4,256 +7%
CNB
197
Czech National Bank
Czech Republic
$27.9M +$1.69M +3,790 +6%
X
198
Xponance
Pennsylvania
$27.9M +$5.98M +13,431 +27%
GFM
199
GF Fund Management
China
$27.7M +$670K +1,505 +2%
Susquehanna International Group
200
Susquehanna International Group
Pennsylvania
$27.7M +$9.39M +21,088 +51%
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