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Vertex Pharmaceuticals
VRTX

Overview Fund Activity

1,536 hedge funds and large institutions have $107B invested in Vertex Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 117 funds opening new positions, 606 increasing their positions, 605 reducing their positions, and 144 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,536
Holders Change
-59
Holders Change %
-3.7%
% of All Funds
20.6%
Holding in Top 10
16
Holding in Top 10 Change
-10
Holding in Top 10 Change %
-38.46%
% of All Funds
0.21%
New
117
Increased
606
Reduced
605
Closed
144
Calls
$930M
Puts
$554M
Net Calls
+$376M
Net Calls Change
+$202M

Top Buyers

1
Capital International Investors
Capital International Investors
California
+$884M
2
Victory Capital Management
Victory Capital Management
Texas
+$836M
3
Capital Research Global Investors
Capital Research Global Investors
California
+$700M
4
Jennison Associates
Jennison Associates
New York
+$485M
5
UBS AM
UBS AM
Illinois
+$226M

Top Sellers

1
Amundi
Amundi
France
-$898M
2
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
-$840M
3
Fidelity Investments
Fidelity Investments
Massachusetts
-$588M
4
Massachusetts Financial Services
Massachusetts Financial Services
Massachusetts
-$330M
5
Wellington Management Group
Wellington Management Group
Massachusetts
-$286M
Name Holding Trade Value Shares
Change 		Shares
Change %
SO
151
STRS Ohio
Ohio
$50.2M +$15.5M +34,907 +45%
HJGA
152
Hardman Johnston Global Advisors
Connecticut
$48.2M -$4.39M -9,855 -8%
Ohio Public Employees Retirement System (OPERS)
153
Ohio Public Employees Retirement System (OPERS)
Ohio
$47.2M -$1.44M -3,227 -3%
State of Tennessee, Department of Treasury
154
State of Tennessee, Department of Treasury
Tennessee
$47.1M +$3.3M +7,410 +8%
CGPCS
155
Capital Group Private Client Services
California
$46.5M +$35.1M +78,905 +308%
Stifel Financial
156
Stifel Financial
Missouri
$45.2M -$2.42M -5,446 -5%
GC
157
Guggenheim Capital
Illinois
$45.1M -$349K -783 -0.8%
Rockefeller Capital Management
158
Rockefeller Capital Management
New York
$44.4M +$3.91M +8,774 +10%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
159
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$43.9M -$22.7M -50,979 -34%
RAM
160
Resona Asset Management
Japan
$42.9M +$2.53M +5,687 +6%
BBVA
161
Banco Bilbao Vizcaya Argentaria
Spain
$41.7M -$2.02M -4,532 -5%
KK
162
KLP Kapitalforvaltning
Norway
$41.3M +$2.27M +5,100 +6%
AssetMark Inc
163
AssetMark Inc
California
$41.1M +$3.16M +7,094 +8%
WP
164
Woodline Partners
California
$40.8M -$27.4M -61,496 -40%
FAF
165
Fjarde Ap-fonden
Sweden
$40.6M +$7.66M +17,200 +23%
CTB
166
Country Trust Bank
Illinois
$40.1M +$139K +312 +0.3%
Thrivent Financial for Lutherans
167
Thrivent Financial for Lutherans
Minnesota
$39.3M +$498K +1,119 +1%
PCH
168
Polar Capital Holdings
United Kingdom
$39M -$16.7M -37,500 -30%
Creative Planning
169
Creative Planning
Kansas
$38.8M -$742K -1,666 -2%
DnB Asset Management
170
DnB Asset Management
Norway
$38.7M -$39.9M -89,600 -51%
State of New Jersey Common Pension Fund D
171
State of New Jersey Common Pension Fund D
New Jersey
$38.6M – – –
Wealth Enhancement Advisory Services
172
Wealth Enhancement Advisory Services
Minnesota
$38M +$1.13M +2,452 +3%
CIBC Asset Management
173
CIBC Asset Management
Ontario, Canada
$36.1M -$1.96M -4,393 -5%
MIM
174
MetLife Investment Management
New Jersey
$34.3M +$2.13M +4,787 +7%
BIAS
175
Beacon Investment Advisory Services
New Jersey
$34.3M -$387K -870 -1%
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