|
1
|
Alphabet Inc
Mountain View,
California
|
$164M
|
–
|
–
|
–
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$84.1M
|
+$11.4M
|
+859,382
|
+16%
|
|
|
3
|
ARK Investment Management
St. Petersburg,
Florida
|
$80.2M
|
-$13.1M
|
-984,640
|
-14%
|
|
|
4
|
|
$71.4M
|
+$12.4M
|
+937,696
|
+21%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$67.7M
|
+$16.3M
|
+1,230,644
|
+32%
|
|
|
6
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$60.8M
|
+$18.6M
|
+1,402,072
|
+44%
|
|
|
7
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$47.2M
|
-$5.62M
|
-423,795
|
-11%
|
|
|
8
|
Fidelity Investments
Boston,
Massachusetts
|
$44.9M
|
-$890K
|
-67,096
|
-2%
|
|
|
9
|
|
$40.6M
|
+$663K
|
+50,000
|
+2%
|
|
|
10
|
Sumitomo Mitsui Trust Group
Minato-Ku, Tokyo,
Japan
|
$34.4M
|
+$2.58M
|
+194,594
|
+8%
|
|
|
11
|
Nikko Asset Management Americas
New York
|
$34.3M
|
+$2.58M
|
+194,594
|
+8%
|
|
|
12
|
Arch Venture Management
Chicago,
Illinois
|
$26.7M
|
–
|
–
|
–
|
|
|
13
|
Novo Holdings A/S
Hellerup,
Denmark
|
$26.6M
|
–
|
–
|
–
|
|
|
14
|
Baker Bros. Advisors
New York
|
$22.5M
|
–
|
–
|
–
|
|
|
15
|
Redmile Group
San Francisco,
California
|
$21.3M
|
-$1.51M
|
-114,154
|
-7%
|
|
|
16
|
|
$19.8M
|
-$7.5M
|
-565,349
|
-27%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$19.3M
|
+$4.23M
|
+319,263
|
+28%
|
|
|
18
|
EcoR1 Capital
San Francisco,
California
|
$16.6M
|
–
|
–
|
–
|
|
|
19
|
Citadel Advisors
Miami,
Florida
|
$15.6M
|
+$9.64M
|
+727,265
|
+162%
|
|
|
20
|
|
$11.8M
|
+$7.14M
|
+538,665
|
+155%
|
|
|
21
|
Nuveen
Charlotte,
North Carolina
|
$11.6M
|
+$5.53M
|
+416,971
|
+91%
|
|
|
22
|
|
$11M
|
+$4.74M
|
+357,254
|
+75%
|
|
|
23
|
BVF Inc
San Francisco,
California
|
$8.63M
|
–
|
–
|
–
|
|
|
24
|
MPM BioImpact
Boston,
Massachusetts
|
$8.47M
|
–
|
–
|
–
|
|
|
25
|
Millennium Management
New York
|
$8.16M
|
+$8.15M
|
+614,430
|
New
|
|
