|
1
|
Alphabet Inc
Mountain View,
California
|
$172M
|
+$22.3M
|
+1,800,000
|
+17%
|
|
|
2
|
ARK Investment Management
St. Petersburg,
Florida
|
$97.9M
|
+$22.6M
|
+1,824,549
|
+35%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$76.3M
|
+$7.92M
|
+638,962
|
+13%
|
|
|
4
|
|
$61.8M
|
+$5.42M
|
+437,082
|
+11%
|
|
|
5
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$55.5M
|
+$17.9M
|
+1,448,003
|
+57%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$53.9M
|
+$7.31M
|
+589,584
|
+18%
|
|
|
7
|
Fidelity Investments
Boston,
Massachusetts
|
$48M
|
-$38.8M
|
-3,132,992
|
-48%
|
|
|
8
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$44.3M
|
+$13.3M
|
+1,069,054
|
+51%
|
|
|
9
|
|
$41.9M
|
+$674K
|
+54,384
|
+2%
|
|
|
10
|
Sumitomo Mitsui Trust Group
Minato-Ku, Tokyo,
Japan
|
$33.4M
|
+$3.1M
|
+250,361
|
+12%
|
|
|
11
|
Nikko Asset Management Americas
New York
|
$33.3M
|
+$3.1M
|
+250,361
|
+12%
|
|
|
12
|
|
$28.7M
|
-$5.55M
|
-447,497
|
-18%
|
|
|
13
|
Arch Venture Management
Chicago,
Illinois
|
$28M
|
–
|
–
|
–
|
|
|
14
|
Novo Holdings A/S
Hellerup,
Denmark
|
$27.9M
|
+$24.8M
|
+2,000,000
|
New
|
|
|
15
|
Redmile Group
San Francisco,
California
|
$24M
|
+$11.3M
|
+908,892
|
+112%
|
|
|
16
|
Baker Bros. Advisors
New York
|
$23.6M
|
+$3.41M
|
+275,000
|
+19%
|
|
|
17
|
EcoR1 Capital
San Francisco,
California
|
$17.4M
|
+$15.5M
|
+1,250,000
|
New
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$15.8M
|
+$958K
|
+77,283
|
+7%
|
|
|
19
|
BVF Inc
San Francisco,
California
|
$9.06M
|
–
|
–
|
–
|
|
|
20
|
MPM BioImpact
Boston,
Massachusetts
|
$8.9M
|
-$2.72M
|
-219,777
|
-26%
|
|
|
21
|
Palo Alto Investors
Palo Alto,
California
|
$8.03M
|
+$7.14M
|
+575,817
|
New
|
|
|
22
|
Woodline Partners
San Francisco,
California
|
$7.26M
|
-$2.12K
|
-171
|
-0%
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$6.88M
|
+$334K
|
+26,968
|
+6%
|
|
|
24
|
|
$6.6M
|
+$3.32M
|
+268,079
|
+130%
|
|
|
25
|
Nuveen
Charlotte,
North Carolina
|
$6.39M
|
+$3.47M
|
+279,604
|
+157%
|
|
