|
1
|
Alphabet Inc
Mountain View,
California
|
$204M
|
-$11.3M
|
-424,925
|
-4%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$134M
|
-$15.3M
|
-576,927
|
-8%
|
|
|
3
|
State Street
Boston,
Massachusetts
|
$86.5M
|
+$44.3M
|
+1,671,215
|
+60%
|
|
|
4
|
ARK Investment Management
St. Petersburg,
Florida
|
$84.5M
|
+$25.8M
|
+971,971
|
+29%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$73.8M
|
+$4.06M
|
+153,212
|
+4%
|
|
|
6
|
|
$69.5M
|
+$5.77M
|
+217,864
|
+6%
|
|
|
7
|
|
$44.3M
|
-$23.5M
|
-887,596
|
-28%
|
|
|
8
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$40.2M
|
+$8.71M
|
+328,552
|
+19%
|
|
|
9
|
Arch Venture Management
Chicago,
Illinois
|
$38.9M
|
–
|
–
|
–
|
|
|
10
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$34.8M
|
+$14.4M
|
+544,834
|
+43%
|
|
|
11
|
|
$34.6M
|
-$3.45M
|
-130,028
|
-7%
|
|
|
12
|
Avidity Partners Management
Dallas,
Texas
|
$30.3M
|
+$13.8M
|
+522,294
|
+50%
|
|
|
13
|
Baker Bros. Advisors
New York
|
$27.4M
|
–
|
–
|
–
|
|
|
14
|
Nikko Asset Management Americas
New York
|
$23.8M
|
+$12M
|
+452,750
|
+58%
|
|
|
15
|
Sumitomo Mitsui Trust Group
Minato-Ku, Tokyo,
Japan
|
$23.8M
|
+$12M
|
+452,750
|
+58%
|
|
|
16
|
Redmile Group
San Francisco,
California
|
$23.6M
|
-$7.5M
|
-283,223
|
-19%
|
|
|
17
|
Novo Holdings A/S
Hellerup,
Denmark
|
$17.6M
|
–
|
–
|
–
|
|
|
18
|
Wellington Management Group
Boston,
Massachusetts
|
$16.6M
|
-$4.02M
|
-151,606
|
-15%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$16.4M
|
+$1.72M
|
+65,021
|
+8%
|
|
|
20
|
MPM BioImpact
Boston,
Massachusetts
|
$15.6M
|
+$4.58M
|
+172,869
|
+27%
|
|
|
21
|
Adage Capital Partners
Boston,
Massachusetts
|
$13.4M
|
+$3.97M
|
+150,000
|
+28%
|
|
|
22
|
BVF Inc
San Francisco,
California
|
$12.6M
|
–
|
–
|
–
|
|
|
23
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$10.8M
|
–
|
–
|
–
|
|
|
24
|
Bank of America
Charlotte,
North Carolina
|
$7.84M
|
+$6.92M
|
+261,198
|
+181%
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$7.74M
|
+$290K
|
+10,947
|
+3%
|
|
