|
1
|
Alphabet Inc
Mountain View,
California
|
$152M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$98.4M
|
-$1.54M
|
-78,606
|
-1%
|
|
|
3
|
ARK Investment Management
St. Petersburg,
Florida
|
$64.6M
|
+$2.28M
|
+116,261
|
+3%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$55.9M
|
+$1.31M
|
+66,826
|
+2%
|
|
|
5
|
|
$51.1M
|
-$932K
|
-47,589
|
-1%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$48.3M
|
-$22M
|
-1,121,272
|
-25%
|
|
|
7
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$34.6M
|
+$6.35M
|
+324,351
|
+16%
|
|
|
8
|
|
$30.6M
|
-$3.33M
|
-170,000
|
-7%
|
|
|
9
|
Arch Venture Management
Chicago,
Illinois
|
$29M
|
–
|
–
|
–
|
|
|
10
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$28.9M
|
+$4.04M
|
+206,477
|
+11%
|
|
|
11
|
|
$27.5M
|
+$2.35M
|
+119,902
|
+7%
|
|
|
12
|
Sumitomo Mitsui Trust Group
Minato-Ku, Tokyo,
Japan
|
$23M
|
+$7.24M
|
+369,547
|
+30%
|
|
|
13
|
Nikko Asset Management Americas
New York
|
$22.4M
|
+$7.24M
|
+369,547
|
+30%
|
|
|
14
|
Baker Bros. Advisors
New York
|
$20.4M
|
–
|
–
|
–
|
|
|
15
|
Avidity Partners Management
Dallas,
Texas
|
$19.5M
|
-$4.18M
|
-213,300
|
-14%
|
|
|
16
|
Novo Holdings A/S
Hellerup,
Denmark
|
$17.3M
|
+$5.66M
|
+288,889
|
+32%
|
|
|
17
|
Redmile Group
San Francisco,
California
|
$16.2M
|
-$1.98M
|
-101,224
|
-8%
|
|
|
18
|
Wellington Management Group
Boston,
Massachusetts
|
$13.5M
|
+$1.45M
|
+74,065
|
+9%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$12.8M
|
+$745K
|
+38,038
|
+4%
|
|
|
20
|
MPM BioImpact
Boston,
Massachusetts
|
$11.6M
|
-$101K
|
-5,160
|
-0.6%
|
|
|
21
|
BVF Inc
San Francisco,
California
|
$9.37M
|
–
|
–
|
–
|
|
|
22
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$8.06M
|
–
|
–
|
–
|
|
|
23
|
|
$7.12M
|
+$6.43M
|
+328,340
|
+198%
|
|
|
24
|
Citadel Advisors
Miami,
Florida
|
$6.13M
|
+$7.6M
|
+388,028
|
+1,053%
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$5.82M
|
+$72.5K
|
+3,700
|
+0.9%
|
|
