|
1
|
Alphabet Inc
Mountain View,
California
|
$661M
|
+$456M
|
+10,974,011
|
New
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
$232M
|
+$165M
|
+3,965,479
|
New
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$208M
|
+$143M
|
+3,449,794
|
New
|
|
|
4
|
|
$183M
|
+$126M
|
+3,038,167
|
New
|
|
|
5
|
Redmile Group
San Francisco,
California
|
$117M
|
+$80.4M
|
+1,936,530
|
New
|
|
|
6
|
Baker Bros. Advisors
New York
|
$85.3M
|
+$58.8M
|
+1,416,530
|
New
|
|
|
7
|
Janus Henderson Group
London,
|
$79.8M
|
+$58.7M
|
+1,413,771
|
New
|
|
|
8
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$58M
|
+$40M
|
+962,826
|
New
|
|
|
9
|
|
$55.4M
|
+$38.2M
|
+920,252
|
New
|
|
|
10
|
RA Capital Management
Boston,
Massachusetts
|
$53M
|
+$36.5M
|
+880,284
|
New
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$48.7M
|
+$34.4M
|
+829,589
|
New
|
|
|
12
|
Novo Holdings A/S
Hellerup,
Denmark
|
$47.8M
|
+$32.9M
|
+793,265
|
New
|
|
|
13
|
Logos Global Management
San Francisco,
California
|
$45.7M
|
+$31.5M
|
+758,265
|
New
|
|
|
14
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$41.3M
|
+$28.4M
|
+685,000
|
New
|
|
|
15
|
Cormorant Asset Management
Boston,
Massachusetts
|
$40.6M
|
+$29.4M
|
+709,224
|
New
|
|
|
16
|
ARK Investment Management
St. Petersburg,
Florida
|
$33M
|
+$22.8M
|
+548,389
|
New
|
|
|
17
|
|
$31.9M
|
+$22M
|
+529,924
|
New
|
|
|
18
|
|
$30.1M
|
+$20.8M
|
+500,000
|
New
|
|
|
19
|
Adage Capital Partners
Boston,
Massachusetts
|
$27.2M
|
+$18.7M
|
+451,680
|
New
|
|
|
20
|
Millennium Management
New York
|
$24.7M
|
+$17M
|
+409,994
|
New
|
|
|
21
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$22.3M
|
+$15.4M
|
+370,000
|
New
|
|
|
22
|
Jennison Associates
New York
|
$22.3M
|
+$15.4M
|
+370,000
|
New
|
|
|
23
|
Woodline Partners
San Francisco,
California
|
$12.5M
|
+$8.59M
|
+206,921
|
New
|
|
|
24
|
|
$7.14M
|
+$4.92M
|
+118,513
|
New
|
|
|
25
|
Darwin Global Management
St. Helier,
Jersey
|
$6.21M
|
+$4.28M
|
+103,013
|
New
|
|
