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Tyra Biosciences

133 hedge funds and large institutions have $1.49B invested in Tyra Biosciences in 2025 Q4 according to their latest regulatory filings, with 29 funds opening new positions, 43 increasing their positions, 38 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding in top 10

Funds holding in top 10:

more capital invested

Capital invested by funds: $ → $

15% more funds holding

Funds holding: 116133 (+17)

13% more repeat investments, than reductions

Existing positions increased: 43 | Existing positions reduced: 38

2.08% more ownership

Funds ownership: 104.39%106.47% (+2.1%)

Holders
133
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
13
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$334K
Puts
$5K
Net Calls
Net Calls Change

Top Buyers

1 +$17M
2 +$10.9M
3 +$7.32M
4
State Street
State Street
Massachusetts
+$5.9M
5
CP
Caligan Partners
New York
+$4.54M

Top Sellers

1 -$28M
2 -$14.1M
3 -$4.72M
4
CPX
Canaan Partners XI
California
-$4.29M
5
Walleye Capital
Walleye Capital
New York
-$4.17M
Name Holding Trade Value Shares
Change
Change in
Stake
A
101
AlphaQuest
New York
$56.2K
CWIG
102
Chung Wu Investment Group
Texas
$52.6K
AIP
103
Ameritas Investment Partners
Nebraska
$52.3K
California State Teachers Retirement System (CalSTRS)
104
California State Teachers Retirement System (CalSTRS)
California
$41.9K
Carson Wealth (CWM LLC)
105
Carson Wealth (CWM LLC)
Nebraska
$41K
SCM
106
Sterling Capital Management
North Carolina
$39.1K
Federated Hermes
107
Federated Hermes
Pennsylvania
$34.1K
Osaic Holdings
108
Osaic Holdings
Arizona
$31.2K
GFM
109
GF Fund Management
China
$27.6K
VCM
110
Versant Capital Management
Arizona
$21.5K
AB
111
Amalgamated Bank
New York
$21K
Royal Bank of Canada
112
Royal Bank of Canada
Ontario, Canada
$19K
SO
113
STRS Ohio
Ohio
$18.4K
GI
114
GAMMA Investing
California
$12.4K
TRCT
115
Tower Research Capital (TRC)
New York
$8.7K
PNC Financial Services Group
116
PNC Financial Services Group
Pennsylvania
$5.47K
Daiwa Securities Group
117
Daiwa Securities Group
Japan
$5K
LFG
118
Larson Financial Group
Missouri
$3.84K
TWD
119
True Wealth Design
Ohio
$3.73K
Optiver Holding
120
Optiver Holding
Netherlands
$3.37K
SAM
121
Smartleaf Asset Management
Massachusetts
$3.23K
AF
122
Allworth Financial
California
$2.63K
Nisa Investment Advisors
123
Nisa Investment Advisors
Missouri
$2.26K
Rockefeller Capital Management
124
Rockefeller Capital Management
New York
$2.21K
SPIA
125
Steward Partners Investment Advisory
New York
$2.02K