TYRA icon

Tyra Biosciences
TYRA

Overview Fund Activity

117 hedge funds and large institutions have $500M invested in Tyra Biosciences in 2025 Q1 according to their latest regulatory filings, with 21 funds opening new positions, 42 increasing their positions, 31 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
117
Holders Change
+4
Holders Change %
+3.54%
% of All Funds
1.59%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.05%
New
21
Increased
42
Reduced
31
Closed
16
Calls
$233K
Puts
$50K
Net Calls
+$183K
Net Calls Change
+$213K

Top Buyers

1
VPC
Vestal Point Capital
New York
+$17.6M
2
KCM
Kynam Capital Management
New Jersey
+$17.4M
3
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$9.25M
4
CC
Commodore Capital
New York
+$8.84M
5
TCM
TCG Crossover Management
California
+$8.45M

Top Sellers

1
BCM
Boxer Capital Management
California
-$28.2M
2
Fidelity Investments
Fidelity Investments
Massachusetts
-$13M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$2.78M
4
NCM
Nantahala Capital Management
Connecticut
-$1.39M
5
ABG
Ally Bridge Group
New York
-$631K
Name Holding Trade Value Shares
Change 		Shares
Change %
AB
101
Amalgamated Bank
New York
$7K +$2.77K +277 +65%
SO
102
STRS Ohio
Ohio
$6.51K – – –
Royal Bank of Canada
103
Royal Bank of Canada
Ontario, Canada
$6K -$860 -97 -13%
CIAM
104
Caitong International Asset Management
Hong Kong
$4.68K +$4.68K +503 New
Federated Hermes
105
Federated Hermes
Pennsylvania
$4.42K -$5.14K -553 -54%
Carson Wealth (CWM LLC)
106
Carson Wealth (CWM LLC)
Nebraska
$4K +$3.26K +312 +439%
Daiwa Securities Group
107
Daiwa Securities Group
Japan
$2K +$2K +173 New
Nisa Investment Advisors
108
Nisa Investment Advisors
Missouri
$1.39K +$1.17K +126 +548%
AF
109
Allworth Financial
California
$1.01K +$1.01K +100 New
PNC Financial Services Group
110
PNC Financial Services Group
Pennsylvania
$539 – – –
CCM
111
Coldstream Capital Management
Washington
$260 +$260 +28 New
SCM
112
Sterling Capital Management
North Carolina
$195 – – –
CA
113
CoreCap Advisors
Michigan
$149 – – –
EWA
114
EverSource Wealth Advisors
Alabama
$84 +$84 +9 New
RIL
115
Rothschild Investment LLC
Illinois
$47 – – –
SS
116
SBI Securities
Japan
$37 -$139 -15 -79%
BCM
117
Boxer Capital Management
California
– -$28.2M -2,027,678 Closed
Adage Capital Partners
118
Adage Capital Partners
Massachusetts
– -$2.78M -200,000 Closed
NCM
119
Nantahala Capital Management
Connecticut
– -$1.39M -100,000 Closed
SFI
120
Susquehanna Fundamental Investments
Pennsylvania
– -$543K -39,093 Closed
PP
121
PDT Partners
New York
– -$283K -20,359 Closed
Squarepoint
122
Squarepoint
New York
– -$253K -18,216 Closed
BFM
123
Boothbay Fund Management
New York
– -$244K -17,560 Closed
Manulife (Manufacturers Life Insurance)
124
Manulife (Manufacturers Life Insurance)
Ontario, Canada
– -$186K -13,368 Closed
Franklin Resources
125
Franklin Resources
California
– -$177K -12,751 Closed
2 3 4
5
6