SLRN

ACELYRIN
SLRN

Overview Fund Activity
Delisted

SLRN was delisted on the 21st of May, 2025.

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101 hedge funds and large institutions have $847M invested in ACELYRIN in 2023 Q3 according to their latest regulatory filings, with 47 funds opening new positions, 20 increasing their positions, 23 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
101
Holders Change
+19
Holders Change %
+23.17%
% of All Funds
1.61%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.11%
New
47
Increased
20
Reduced
23
Closed
28
Calls
$3.2M
Puts
$5.7M
Net Calls
-$2.5M
Net Calls Change
-$5.21M

Top Buyers

1
State Street
State Street
Massachusetts
$20.1M
2
Janus Henderson Group
Janus Henderson Group
United Kingdom
$16.4M
3
Fidelity Investments
Fidelity Investments
Massachusetts
$89.9M
4
Goldman Sachs
Goldman Sachs
New York
$18.1M
5
EC
EcoR1 Capital
California
$14.3M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
$0
2
APM
Avidity Partners Management
Texas
$0
3
Millennium Management
Millennium Management
New York
$0
4
DM
Deerfield Management
New York
$0
5
AllianceBernstein
AllianceBernstein
Tennessee
$254K
Name Holding Trade Value Shares
Change 		Shares
Change %
Citigroup
51
Citigroup
New York
$745K +$745K +73,269 New
GCM
52
Ghisallo Capital Management
Massachusetts
$712K – – –
Ameriprise
53
Ameriprise
Minnesota
$692K -$3.42M -336,750 -83%
Swiss National Bank
54
Swiss National Bank
Switzerland
$652K +$652K +64,100 New
Wells Fargo
55
Wells Fargo
California
$576K +$574K +56,451 +25,201%
Manulife (Manufacturers Life Insurance)
56
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$566K +$139K +13,692 +33%
FAM
57
Fred Alger Management
New York
$541K -$9.73M -956,843 -95%
CM
58
Caption Management
Oklahoma
$512K +$512K +50,377 New
Alyeska Investment Group
59
Alyeska Investment Group
Illinois
$509K – – –
Nuveen Asset Management
60
Nuveen Asset Management
Illinois
$457K +$457K +44,936 New
RhumbLine Advisers
61
RhumbLine Advisers
Massachusetts
$449K +$449K +44,152 New
State of Wisconsin Investment Board
62
State of Wisconsin Investment Board
Wisconsin
$382K +$382K +37,590 New
California State Teachers Retirement System (CalSTRS)
63
California State Teachers Retirement System (CalSTRS)
California
$340K +$340K +33,463 New
Walleye Trading
64
Walleye Trading
New York
$320K +$320K +31,428 New
Legal & General Group
65
Legal & General Group
United Kingdom
$312K +$312K +30,646 New
PA
66
Profund Advisors
Maryland
$297K +$297K +29,232 New
CS
67
Credit Suisse
Switzerland
$280K +$280K +27,489 New
AllianceBernstein
68
AllianceBernstein
Tennessee
$254K -$11.4M -1,118,344 -98%
AFP
69
Ausdal Financial Partners
Iowa
$214K +$214K +21,000 New
Mirae Asset Global Investments
70
Mirae Asset Global Investments
South Korea
$205K +$205K +20,196 New
JF
71
Jump Financial
Illinois
$199K -$41.6K -4,092 -17%
Man Group
72
Man Group
United Kingdom
$193K – – –
RJA
73
Raymond James & Associates
Florida
$189K +$189K +18,556 New
MIM
74
MetLife Investment Management
New Jersey
$185K +$185K +18,159 New
Invesco
75
Invesco
Georgia
$183K +$183K +17,953 New
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