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SLN

Silence Therapeutics

59 hedge funds and large institutions have $60.6M invested in Silence Therapeutics in 2025 Q1 according to their latest regulatory filings, with 5 funds opening new positions, 18 increasing their positions, 25 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

2.26% less ownership

Funds ownership: 17.73%15.47% (-2.3%)

9% less funds holding

Funds holding: 6559 (-6)

28% less repeat investments, than reductions

Existing positions increased: 18 | Existing positions reduced: 25

43% less call options, than puts

Call options by funds: $4K | Put options by funds: $7K

55% less first-time investments, than exits

New positions opened: 5 | Existing positions closed: 11

64% less capital invested

Capital invested by funds: $168M → $60.6M (-$108M)

100% less funds holding in top 10

Funds holding in top 10: 30 (-3)

Holders
59
Holders Change
-6
Holders Change %
-9.23%
% of All Funds
0.79%
Holding in Top 10
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-100%
% of All Funds
New
5
Increased
18
Reduced
25
Closed
11
Calls
$4K
Puts
$7K
Net Calls
-$3K
Net Calls Change
+$39K
Name Holding Trade Value Shares
Change
Change in
Stake
Two Sigma Investments
26
Two Sigma Investments
New York
$214K -$322K -66,044 -46%
Osaic Holdings
27
Osaic Holdings
Arizona
$201K +$150K +30,630 +75%
Bank of America
28
Bank of America
North Carolina
$183K -$2.12M -434,180 -87%
UOC
29
UBS O'Connor
Illinois
$177K -$324K -66,351 -51%
Citadel Advisors
30
Citadel Advisors
Florida
$176K -$1.08M -220,296 -78%
Citigroup
31
Citigroup
New York
$172K +$2.78K +569 +0.9%
Two Sigma Advisers
32
Two Sigma Advisers
New York
$139K -$242K -49,600 -50%
SC
33
Shay Capital
New York
$135K +$233K +47,728 New
JP Morgan Chase
34
JP Morgan Chase
New York
$99.9K +$154K +31,621 +834%
Geode Capital Management
35
Geode Capital Management
Massachusetts
$83K
JF
36
Jump Financial
Illinois
$74.3K +$129K +26,351 New
VIA
37
Virtus Investment Advisers
Connecticut
$70.1K +$121K +24,872 New
Goldman Sachs
38
Goldman Sachs
New York
$68.7K -$61.1K -12,510 -34%
Qube Research & Technologies (QRT)
39
Qube Research & Technologies (QRT)
United Kingdom
$53.3K -$175K -35,833 -65%
ACM
40
ADAR1 Capital Management
Texas
$52.6K +$3.14K +643 +4%
RG
41
Rathbones Group
United Kingdom
$51.9K
Point72 Asset Management
42
Point72 Asset Management
Connecticut
$45.2K -$3.01M -617,068 -97%
Acadian Asset Management
43
Acadian Asset Management
Massachusetts
$34K -$35.7K -7,314 -38%
CUAMC
44
China Universal Asset Management Company
China
$26.6K -$2.59K -531 -5%
CSS
45
Cubist Systematic Strategies
Connecticut
$20.8K -$483K -98,956 -93%
Barclays
46
Barclays
United Kingdom
$19.3K +$3.56K +728 +12%
FIA
47
FNY Investment Advisers
New York
$19K -$51.3K -10,515 -60%
BNP Paribas Financial Markets
48
BNP Paribas Financial Markets
France
$13.5K +$14.7K +3,004 +168%
Royal Bank of Canada
49
Royal Bank of Canada
Ontario, Canada
$12K +$13.4K +2,748 +181%
GI
50
GAMMA Investing
California
$10K -$12.4K -2,532 -42%

SLN Hedge Fund Activity: Q1 2025 in Review

59 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Silence Therapeutics (SLN) for Q1 2025, worth a combined $60.6M — down 64% from $168M a quarter earlier.

Sellers outnumbered buyers: 11 funds closed out of SLN and 5 opened new positions — a net loss of 6 holders — while 25 trimmed existing stakes and 18 added.

The largest buyer was Saturn V Capital Management, adding an estimated $1.65M. The largest seller was Eventide Asset Management, exiting entirely with an estimated $4.4M sold.

  • 59 institutional investors held Silence Therapeutics (SLN) as of Q1 2025, down from 65 in Q4 2024.
  • Funds reported $60.6M of Silence Therapeutics stock for Q1 2025, down 64% quarter-over-quarter.
  • 5 funds opened new Silence Therapeutics positions in Q1 2025 and 11 closed out, a net change of -6 holders.
  • The largest Silence Therapeutics buyer in Q1 2025 was Saturn V Capital Management, an estimated $1.65M added.
  • The largest Silence Therapeutics seller in Q1 2025 was Eventide Asset Management, an estimated $4.4M sold.

Based on aggregated 13F filings for Q1 2025.