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SLN

Silence Therapeutics
SLN

65 hedge funds and large institutions have $168M invested in Silence Therapeutics in 2024 Q4 according to their latest regulatory filings, with 16 funds opening new positions, 24 increasing their positions, 13 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

85% more repeat investments, than reductions

Existing positions increased: 24 | Existing positions reduced: 13

2.41% less ownership

Funds ownership: 20.14% → 17.73% (-2.4%)

6% less funds holding

Funds holding: 69 → 65 (-4)

20% less first-time investments, than exits

New positions opened: 16 | Existing positions closed: 20

40% less funds holding in top 10

Funds holding in top 10: 5 → 3 (-2)

66% less capital invested

Capital invested by funds: $493M → $168M (-$325M)

93% less call options, than puts

Call options by funds: $3K | Put options by funds: $45K

Holders
65
Holders Change
-4
Holders Change %
-5.8%
% of All Funds
0.86%
Holding in Top 10
3
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-40%
% of All Funds
0.04%
New
16
Increased
24
Reduced
13
Closed
20
Calls
$3K
Puts
$45K
Net Calls
-$42K
Net Calls Change
-$14K

Top Buyers

Rank Fund Capital Flow
1
Morgan Stanley
Morgan Stanley
New York
+$12.2M
2
NCM
Nantahala Capital Management
Connecticut
+$11M
3
RG
Redmile Group
California
+$6.45M
4
Bank of America
Bank of America
North Carolina
+$6.43M
5
Marshall Wace
Marshall Wace
United Kingdom
+$4.14M

Top Sellers

Rank Fund Capital Flow
1
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$19.8M
2
DTC
Deep Track Capital
Connecticut
-$18.2M
3
PCH
Polar Capital Holdings
United Kingdom
-$18.2M
4
LOAMU
Lombard Odier Asset Management (USA)
New York
-$10.4M
5
Millennium Management
Millennium Management
New York
-$8.22M
Name Holding Trade Value Shares
Change 		Change in
Stake
IHAM
26
Integral Health Asset Management
New York
$1.38M +$2.58M +200,000 New
MCM
27
M28 Capital Management
Connecticut
$1.27M – – –
HSBC Holdings
28
HSBC Holdings
United Kingdom
$1.19M -$64.5K -5,000 -3%
Two Sigma Investments
29
Two Sigma Investments
New York
$977K -$353K -27,340 -16%
UOC
30
UBS O'Connor
Illinois
$887K +$559K +43,289 +51%
SSA
31
Schonfeld Strategic Advisors
New York
$848K -$552K -42,800 -26%
CSS
32
Cubist Systematic Strategies
Connecticut
$731K +$774K +60,015 +130%
Two Sigma Advisers
33
Two Sigma Advisers
New York
$680K +$200K +15,500 +19%
Bank of Montreal
34
Bank of Montreal
Ontario, Canada
$447K -$3.25K -252 -0.4%
TI
35
Trexquant Investment
Connecticut
$438K +$821K +63,663 New
Citigroup
36
Citigroup
New York
$416K +$28K +2,169 +4%
Qube Research & Technologies (QRT)
37
Qube Research & Technologies (QRT)
United Kingdom
$377K +$459K +35,550 +185%
Osaic Holdings
38
Osaic Holdings
Arizona
$281K +$358K +27,708 +211%
Goldman Sachs
39
Goldman Sachs
New York
$254K +$80.7K +6,253 +20%
Walleye Capital
40
Walleye Capital
New York
$250K +$470K +36,397 New
Geode Capital Management
41
Geode Capital Management
Massachusetts
$202K – – –
Verition Fund Management
42
Verition Fund Management
Connecticut
$166K +$164K +12,733 +112%
YIH
43
Y-Intercept (HK)
Hong Kong
$146K +$1.79K +139 +0.7%
COPPSERS
44
Commonwealth of Pennsylvania Public School Employees Retirement System
Pennsylvania
$134K +$251K +19,467 New
Acadian Asset Management
45
Acadian Asset Management
Massachusetts
$133K +$251K +19,467 New
RG
46
Rathbones Group
United Kingdom
$127K – – –
ACM
47
ADAR1 Capital Management
Texas
$124K -$288K -22,290 -55%
FIA
48
FNY Investment Advisers
New York
$120K +$226K +17,515 New
Ameriprise
49
Ameriprise
Minnesota
$113K +$211K +16,360 New
CIS
50
Custom Index Systems
New York
$81.6K -$33K -2,554 -18%
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SLN Hedge Fund Activity: Q4 2024 in Review

65 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Silence Therapeutics (SLN) for Q4 2024, worth a combined $168M — down 66% from $493M a quarter earlier.

Sellers outnumbered buyers: 20 funds closed out of SLN and 16 opened new positions — a net loss of 4 holders — while 13 trimmed existing stakes and 24 added.

The largest buyer was Morgan Stanley, adding an estimated $12.2M. The largest seller was Janus Henderson Group, exiting entirely with an estimated $19.8M sold.

  • 65 institutional investors held Silence Therapeutics (SLN) as of Q4 2024, down from 69 in Q3 2024.
  • Funds reported $168M of Silence Therapeutics stock for Q4 2024, down 66% quarter-over-quarter.
  • 16 funds opened new Silence Therapeutics positions in Q4 2024 and 20 closed out, a net change of -4 holders.
  • The largest Silence Therapeutics buyer in Q4 2024 was Morgan Stanley, an estimated $12.2M added.
  • The largest Silence Therapeutics seller in Q4 2024 was Janus Henderson Group, an estimated $19.8M sold.

Based on aggregated 13F filings for Q4 2024.