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QURE

Name Holding Trade Value Shares
Change 		Change in
Stake
HNB
176
Huntington National Bank
Ohio
$23 – – –
DTC
177
Deep Track Capital
Connecticut
– -$17.4M -865,767 Closed
ACM
178
Aquilo Capital Management
California
– -$12.8M -637,526 Closed
Adage Capital Partners
179
Adage Capital Partners
Massachusetts
– -$12.7M -630,000 Closed
IHAM
180
Integral Health Asset Management
New York
– -$9.47M -500,000 Closed
MB
181
MPM BioImpact
Massachusetts
– -$7.01M -348,224 Closed
Assenagon Asset Management
182
Assenagon Asset Management
Luxembourg
– -$6.66M -330,617 Closed
Lord, Abbett & Co
183
Lord, Abbett & Co
New Jersey
– -$5.21M -258,571 Closed
Voloridge Investment Management
184
Voloridge Investment Management
Florida
– -$4.72M -234,204 Closed
TLP
185
Tri Locum Partners
New York
– -$4.58M -227,273 Closed
Walleye Capital
186
Walleye Capital
New York
– -$2.11M -104,642 Closed
JAM
187
Jupiter Asset Management
United Kingdom
– -$1.71M -85,044 Closed
First Trust Advisors
188
First Trust Advisors
Illinois
– -$1.66M -82,626 Closed
ECM
189
Endurant Capital Management
California
– -$1.43M -71,040 Closed
MFS
190
Mirabella Financial Services
United Kingdom
– -$1.32M -53,198 Closed
JF
191
Jump Financial
Illinois
– -$960K -47,689 Closed
DekaBank Deutsche Girozentrale
192
DekaBank Deutsche Girozentrale
Germany
– -$767K -39,400 Closed
GCP
193
GSA Capital Partners
United Kingdom
– -$440K -21,826 Closed
Qube Research & Technologies (QRT)
194
Qube Research & Technologies (QRT)
United Kingdom
– -$409K -20,320 Closed
Marshall Wace
195
Marshall Wace
United Kingdom
– -$382K -18,944 Closed
Walleye Trading
196
Walleye Trading
New York
– -$311K -16,416 Closed
Nomura Holdings
197
Nomura Holdings
Japan
– -$260K -12,896 Closed
FIM
198
Freedom Investment Management
Connecticut
– -$212K -10,510 Closed
SG Americas Securities
199
SG Americas Securities
New York
– -$208K -10,342 Closed
CC
200
Centiva Capital
New York
– -$55.1K -2,738 Closed
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8
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