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QURE

Name Holding Trade Value Shares
Change 		Change in
Stake
Lazard Asset Management
176
Lazard Asset Management
New York
$1K +$2.3K +39 New
EAM
177
Eagle Asset Management
Florida
– -$20.1M -422,739 Closed
SIG
178
Senator Investment Group
New York
– -$19M -400,000 Closed
APM
179
Avidity Partners Management
Texas
– -$11.2M -237,000 Closed
SPC
180
Slate Path Capital
New York
– -$6.64M -140,000 Closed
RCM
181
RA Capital Management
Massachusetts
– -$3.9M -82,180 Closed
SMH
182
Sanders Morris Harris
Texas
– -$4.3M -71,000 Closed
RCG
183
Rock Creek Group
District of Columbia
– -$2.85M -60,000 Closed
Assenagon Asset Management
184
Assenagon Asset Management
Luxembourg
– -$2.54M -53,607 Closed
ACM
185
Asymmetry Capital Management
California
– -$1.53M -32,331 Closed
CAC
186
Cowen and Company
New York
– -$1.45M -30,599 Closed
VC
187
Vivo Capital
California
– -$1.09M -22,932 Closed
ACM
188
Atika Capital Management
New York
– -$1.04M -22,000 Closed
TAL
189
TIG Advisors LLC
New York
– -$949K -20,000 Closed
FCMI
190
Foresite Capital Management IV
California
– -$905K -19,082 Closed
PC
191
PA Capital
Virginia
– -$817K -17,226 Closed
Balyasny Asset Management
192
Balyasny Asset Management
Illinois
– -$747K -15,745 Closed
AI
193
Atria Investments
North Carolina
– -$367K -7,724 Closed
SG Americas Securities
194
SG Americas Securities
New York
– -$362K -7,636 Closed
Squarepoint
195
Squarepoint
New York
– -$292K -6,155 Closed
MF
196
Magnetar Financial
Illinois
– -$291K -6,127 Closed
TI
197
Trexquant Investment
Connecticut
– -$257K -5,409 Closed
AAP
198
Ardsley Advisory Partners
Connecticut
– -$237K -5,000 Closed
GT
199
Glenmede Trust
Pennsylvania
– -$289K -4,041 Closed
Victory Capital Management
200
Victory Capital Management
Texas
– -$188K -3,971 Closed
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