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uniQure
QURE

Overview Fund Activity

143 hedge funds and large institutions have $738M invested in uniQure in 2025 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 44 increasing their positions, 48 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
143
Holders Change
+3
Holders Change %
+2.14%
% of All Funds
1.92%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
32
Increased
44
Reduced
48
Closed
29
Calls
$81.3M
Puts
$19.1M
Net Calls
+$62.1M
Net Calls Change
+$44.9M

Top Buyers

1
JFG
Jefferies Financial Group
New York
+$29.2M
2
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$20.8M
3
ACA
Avoro Capital Advisors
New York
+$20.2M
4
SI
Sofinnova Investments
California
+$14.1M
5
RI
RTW Investments
New York
+$12.4M

Top Sellers

1
VPC
Vestal Point Capital
New York
-$15.2M
2
NCM
Nantahala Capital Management
Connecticut
-$9.82M
3
Schroder Investment Management Group
Schroder Investment Management Group
United Kingdom
-$6.93M
4
PHS
PFM Health Sciences
California
-$5.93M
5
CCM
Catalio Capital Management
New York
-$5.76M
Name Holding Trade Value Shares
Change 		Shares
Change %
Janus Henderson Group
101
Janus Henderson Group
United Kingdom
$236K +$236K +16,900 New
Mitsubishi UFJ Asset Management
102
Mitsubishi UFJ Asset Management
Japan
$215K +$215K +15,420 New
FCM
103
Farallon Capital Management
California
$195K – – –
PA
104
Profund Advisors
Maryland
$191K -$36.7K -2,632 -16%
Wolverine Trading
105
Wolverine Trading
Illinois
$191K +$41K +2,956 +27%
VPIM
106
Vanguard Personalized Indexing Management
California
$178K -$12.5K -895 -7%
TCWM
107
Total Clarity Wealth Management
Illinois
$174K -$40.4K -2,900 -19%
CHAM
108
Clear Harbor Asset Management
Connecticut
$171K -$17.4K -1,250 -9%
ASRS
109
Arizona State Retirement System
Arizona
$165K +$165K +11,824 New
CUAMC
110
China Universal Asset Management Company
China
$153K -$8.06K -578 -5%
Wells Fargo
111
Wells Fargo
California
$153K -$19.3K -1,388 -11%
Teacher Retirement System of Texas
112
Teacher Retirement System of Texas
Texas
$151K +$151K +10,808 New
KK
113
KLP Kapitalforvaltning
Norway
$117K +$117K +8,400 New
TRCT
114
Tower Research Capital (TRC)
New York
$98.8K +$77.2K +5,538 +358%
VIA
115
Virtus Investment Advisers
Connecticut
$82K -$70K -5,025 -46%
AWM
116
Activest Wealth Management
Florida
$69.7K – – –
FFWM
117
Future Financial Wealth Management
Ohio
$55.8K – – –
Mirae Asset Global Investments
118
Mirae Asset Global Investments
South Korea
$29.5K +$4.27K +306 +17%
SS
119
SBI Securities
Japan
$24.1K +$14K +1,003 +138%
PHK
120
Point72 Hong Kong
Hong Kong
$20.4K +$20.4K +1,465 New
GFM
121
GF Fund Management
China
$17.4K – – –
Toronto Dominion Bank
122
Toronto Dominion Bank
Ontario, Canada
$16.7K +$16.7K +1,200 New
C
123
Covestor
United Kingdom
$16K +$16K +1,183 New
FIA
124
FNY Investment Advisers
New York
$13K +$13K +936 New
National Bank of Canada
125
National Bank of Canada
Quebec, Canada
$10.8K -$2.62K -188 -19%
3 4
5
6 7