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uniQure
QURE

Overview Fund Activity

143 hedge funds and large institutions have $738M invested in uniQure in 2025 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 44 increasing their positions, 48 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
143
Holders Change
+3
Holders Change %
+2.14%
% of All Funds
1.92%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
32
Increased
44
Reduced
48
Closed
29
Calls
$81.3M
Puts
$19.1M
Net Calls
+$62.1M
Net Calls Change
+$44.9M

Top Buyers

1
JFG
Jefferies Financial Group
New York
+$29.2M
2
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$20.8M
3
ACA
Avoro Capital Advisors
New York
+$20.2M
4
SI
Sofinnova Investments
California
+$14.1M
5
RI
RTW Investments
New York
+$12.4M

Top Sellers

1
VPC
Vestal Point Capital
New York
-$15.2M
2
NCM
Nantahala Capital Management
Connecticut
-$9.82M
3
Schroder Investment Management Group
Schroder Investment Management Group
United Kingdom
-$6.93M
4
PHS
PFM Health Sciences
California
-$5.93M
5
CCM
Catalio Capital Management
New York
-$5.76M
Name Holding Trade Value Shares
Change 		Shares
Change %
SAM
76
Sectoral Asset Management
Quebec, Canada
$773K -$29.3K -2,100 -4%
Jane Street
77
Jane Street
New York
$703K +$182K +13,034 +35%
CC
78
Centiva Capital
New York
$697K +$697K +50,000 New
Susquehanna International Group
79
Susquehanna International Group
Pennsylvania
$673K +$96.7K +6,936 +17%
HT
80
Headlands Technologies
Illinois
$592K +$445K +31,948 +304%
Raymond James Financial
81
Raymond James Financial
Florida
$562K -$26.4K -1,897 -4%
MCM
82
Massar Capital Management
Connecticut
$558K – – –
California State Teachers Retirement System (CalSTRS)
83
California State Teachers Retirement System (CalSTRS)
California
$540K +$540K +38,707 New
SFI
84
Susquehanna Fundamental Investments
Pennsylvania
$537K – – –
Mirae Asset Global ETFs Holdings
85
Mirae Asset Global ETFs Holdings
Hong Kong
$518K -$471K -33,814 -48%
Legal & General Group
86
Legal & General Group
United Kingdom
$497K +$497K +35,621 New
ACM
87
Aquatic Capital Management
Illinois
$492K +$344K +24,672 +233%
BFM
88
Boothbay Fund Management
New York
$469K -$58K -4,160 -11%
HWAM
89
Hennion & Walsh Asset Management
New Jersey
$423K +$423K +30,369 New
HF
90
HRT Financial
New York
$396K +$396K +28,420 New
EGM
91
Engineers Gate Manager
New York
$389K +$389K +27,904 New
D.E. Shaw & Co
92
D.E. Shaw & Co
New York
$384K +$384K +27,531 New
DnB Asset Management
93
DnB Asset Management
Norway
$351K -$2.24K -161 -0.6%
MCP
94
Militia Capital Partners
Nevada
$309K +$309K +22,200 New
Corient Private Wealth
95
Corient Private Wealth
Florida
$296K +$148K +10,630 +100%
Citigroup
96
Citigroup
New York
$286K -$1.03M -73,715 -78%
VF
97
Virtu Financial
New York
$277K +$277K +19,850 New
Zurich Cantonal Bank
98
Zurich Cantonal Bank
Switzerland
$276K +$242K +17,348 +706%
BG
99
Bellevue Group
Switzerland
$273K -$40.3K -2,890 -13%
AG
100
Algert Global
California
$270K +$270K +19,340 New
2 3
4
5 6