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uniQure

141 hedge funds and large institutions have $533M invested in uniQure in 2025 Q1 according to their latest regulatory filings, with 24 funds opening new positions, 53 increasing their positions, 37 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

307% more call options, than puts

Call options by funds: $22.9M | Put options by funds: $5.62M

43% more repeat investments, than reductions

Existing positions increased: 53 | Existing positions reduced: 37

20% more first-time investments, than exits

New positions opened: 24 | Existing positions closed: 20

7.08% more ownership

Funds ownership: 85.53%92.61% (+7.1%)

2% more funds holding

Funds holding: 138141 (+3)

28% less capital invested

Capital invested by funds: $736M → $533M (-$203M)

50% less funds holding in top 10

Funds holding in top 10: 63 (-3)

Holders
141
Holders Change
+3
Holders Change %
+2.17%
% of All Funds
1.89%
Holding in Top 10
3
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-50%
% of All Funds
0.04%
New
24
Increased
53
Reduced
37
Closed
20
Calls
$22.9M
Puts
$5.62M
Net Calls
+$17.3M
Net Calls Change
-$21.1M
Name Holding Trade Value Shares
Change
Change in
Stake
SPC
76
Sigma Planning Corp
Michigan
$489K -$8.34K -595 -1%
AllianceBernstein
77
AllianceBernstein
Tennessee
$450K -$2.26M -161,420 -79%
Raymond James Financial
78
Raymond James Financial
Florida
$447K -$957K -68,274 -62%
SSA
79
Schonfeld Strategic Advisors
New York
$447K -$6.93M -494,275 -92%
Susquehanna International Group
80
Susquehanna International Group
Pennsylvania
$438K -$6.25M -445,462 -92%
CF
81
Cantor Fitzgerald
New York
$427K +$565K +40,300 New
MCM
82
Massar Capital Management
Connecticut
$424K +$561K +40,000 New
SFI
83
Susquehanna Fundamental Investments
Pennsylvania
$408K
JF
84
Jump Financial
Illinois
$405K -$2.43M -173,576 -82%
BFM
85
Boothbay Fund Management
New York
$400K +$198K +14,113 +60%
Jane Street
86
Jane Street
New York
$396K +$221K +15,727 +73%
XT
87
XTX Topco
Cayman Islands
$392K +$291K +20,720 +127%
DP
88
Diadema Partners
New Jersey
$387K +$512K +36,500 New
PP
89
PDT Partners
New York
$329K -$715 -51 -0.2%
GCP
90
GSA Capital Partners
United Kingdom
$304K +$402K +28,643 New
TCWM
91
Total Clarity Wealth Management
Illinois
$271K
PWM
92
Palumbo Wealth Management
New York
$269K +$9.13K +651 +3%
DnB Asset Management
93
DnB Asset Management
Norway
$268K +$46.2K +3,292 +15%
Balyasny Asset Management
94
Balyasny Asset Management
Illinois
$264K -$4.69M -334,245 -93%
Nomura Holdings
95
Nomura Holdings
Japan
$245K +$324K +23,081 New
BG
96
Bellevue Group
Switzerland
$239K
PEAK6
97
PEAK6
Illinois
$234K +$54.3K +3,870 +21%
CM
98
Caption Management
Oklahoma
$216K +$285K +20,359 New
PA
99
Profund Advisors
Maryland
$173K +$229K +16,348 New
OAC
100
OMERS Administration Corp
Ontario, Canada
$152K +$201K +14,300 New

QURE Hedge Fund Activity: Q1 2025 in Review

141 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in uniQure (QURE) for Q1 2025, worth a combined $533M — down 28% from $736M a quarter earlier.

Buyers outnumbered sellers: 24 funds opened new QURE positions and 20 closed out — a net gain of 4 holders — while 53 added to existing stakes and 37 trimmed.

The largest buyer was RTW Investments, adding an estimated $47.1M. The largest seller was Point72 Asset Management, cutting an estimated $23M.

  • 141 institutional investors held uniQure (QURE) as of Q1 2025, up from 138 in Q4 2024.
  • Funds reported $533M of uniQure stock for Q1 2025, down 28% quarter-over-quarter.
  • 24 funds opened new uniQure positions in Q1 2025 and 20 closed out, a net change of +4 holders.
  • The largest uniQure buyer in Q1 2025 was RTW Investments, an estimated $47.1M added.
  • The largest uniQure seller in Q1 2025 was Point72 Asset Management, an estimated $23M sold.

Based on aggregated 13F filings for Q1 2025.