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uniQure
QURE

Overview Fund Activity

143 hedge funds and large institutions have $738M invested in uniQure in 2025 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 44 increasing their positions, 48 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
143
Holders Change
+3
Holders Change %
+2.14%
% of All Funds
1.92%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
32
Increased
44
Reduced
48
Closed
29
Calls
$81.3M
Puts
$19.1M
Net Calls
+$62.1M
Net Calls Change
+$44.9M

Top Buyers

1
JFG
Jefferies Financial Group
New York
+$29.2M
2
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$20.8M
3
ACA
Avoro Capital Advisors
New York
+$20.2M
4
SI
Sofinnova Investments
California
+$14.1M
5
RI
RTW Investments
New York
+$12.4M

Top Sellers

1
VPC
Vestal Point Capital
New York
-$15.2M
2
NCM
Nantahala Capital Management
Connecticut
-$9.82M
3
Schroder Investment Management Group
Schroder Investment Management Group
United Kingdom
-$6.93M
4
PHS
PFM Health Sciences
California
-$5.93M
5
CCM
Catalio Capital Management
New York
-$5.76M
Name Holding Trade Value Shares
Change 		Shares
Change %
SSA
51
Schonfeld Strategic Advisors
New York
$1.88M +$1.29M +92,801 +220%
Millennium Management
52
Millennium Management
New York
$1.85M -$1.85M -133,002 -50%
Northern Trust
53
Northern Trust
Illinois
$1.75M +$373K +26,789 +27%
VC
54
Voss Capital
Texas
$1.74M +$1.74M +125,000 New
IC
55
Ikarian Capital
Texas
$1.67M +$1.67M +119,986 New
UBS AM
56
UBS AM
Illinois
$1.54M +$1.54M +110,576 New
Russell Investments Group
57
Russell Investments Group
United Kingdom
$1.48M -$2.75M -197,142 -65%
Point72 Asset Management
58
Point72 Asset Management
Connecticut
$1.48M -$336K -24,136 -19%
SC
59
Shay Capital
New York
$1.39M +$244K +17,534 +21%
BC
60
Birchview Capital
Vermont
$1.38M +$139K +10,000 +11%
SG Americas Securities
61
SG Americas Securities
New York
$1.32M +$1.32M +94,759 New
Verition Fund Management
62
Verition Fund Management
Connecticut
$1.29M -$55K -3,943 -4%
Barclays
63
Barclays
United Kingdom
$1.24M +$297K +21,270 +31%
Diamond Hill Capital Management
64
Diamond Hill Capital Management
Ohio
$1.15M – – –
Swiss National Bank
65
Swiss National Bank
Switzerland
$1.08M +$1.08M +77,500 New
SC
66
SummitTX Capital
Texas
$1.08M +$1.08M +77,495 New
MAM
67
Monaco Asset Management
Monaco
$976K -$69.7K -5,000 -7%
Rafferty Asset Management
68
Rafferty Asset Management
New York
$959K -$192K -13,782 -17%
VOYA Investment Management
69
VOYA Investment Management
Georgia
$938K +$254K +18,205 +37%
Stifel Financial
70
Stifel Financial
Missouri
$934K +$156K +11,213 +20%
Simplex Trading
71
Simplex Trading
Illinois
$895K +$233K +16,735 +35%
Group One Trading
72
Group One Trading
Illinois
$888K +$838K +60,136 +1,696%
UOC
73
UBS O'Connor
Illinois
$885K -$717K -51,414 -45%
YIH
74
Y-Intercept (HK)
Hong Kong
$872K +$872K +62,538 New
MMEA
75
Main Management ETF Advisors
California
$786K +$12.7K +912 +2%
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3
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