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uniQure
QURE

141 hedge funds and large institutions have $533M invested in uniQure in 2025 Q1 according to their latest regulatory filings, with 24 funds opening new positions, 53 increasing their positions, 37 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

307% more call options, than puts

Call options by funds: $22.9M | Put options by funds: $5.62M

43% more repeat investments, than reductions

Existing positions increased: 53 | Existing positions reduced: 37

20% more first-time investments, than exits

New positions opened: 24 | Existing positions closed: 20

7.08% more ownership

Funds ownership: 85.53% → 92.61% (+7.1%)

2% more funds holding

Funds holding: 138 → 141 (+3)

28% less capital invested

Capital invested by funds: $736M → $533M (-$203M)

50% less funds holding in top 10

Funds holding in top 10: 6 → 3 (-3)

Holders
141
Holders Change
+3
Holders Change %
+2.17%
% of All Funds
1.89%
Holding in Top 10
3
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-50%
% of All Funds
0.04%
New
24
Increased
53
Reduced
37
Closed
20
Calls
$22.9M
Puts
$5.62M
Net Calls
+$17.3M
Net Calls Change
-$21.1M

Top Buyers

Rank Fund Capital Flow
1
RI
RTW Investments
New York
+$47.1M
2
VPC
Vestal Point Capital
New York
+$24.8M
3
State Street
State Street
Massachusetts
+$14.5M
4
Citadel Advisors
Citadel Advisors
Florida
+$10.8M
5
Aberdeen Group
Aberdeen Group
United Kingdom
+$9.9M

Top Sellers

Rank Fund Capital Flow
1
Point72 Asset Management
Point72 Asset Management
Connecticut
-$23M
2
Marshall Wace
Marshall Wace
United Kingdom
-$9.4M
3
SSA
Schonfeld Strategic Advisors
New York
-$6.93M
4
Susquehanna International Group
Susquehanna International Group
Pennsylvania
-$6.25M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
-$4.69M
Name Holding Trade Value Shares
Change 		Change in
Stake
Ameriprise
26
Ameriprise
Minnesota
$5.83M +$251K +17,900 +3%
SI
27
Sofinnova Investments
California
$5.79M +$7.65M +545,771 New
Voloridge Investment Management
28
Voloridge Investment Management
Florida
$5.31M +$4.54M +323,798 +183%
Invesco
29
Invesco
Georgia
$5.14M -$1.8M -128,296 -21%
BNP Paribas Financial Markets
30
BNP Paribas Financial Markets
France
$5.1M +$184K +13,093 +3%
PFCS
31
Pale Fire Capital SE
Czech Republic
$4.9M -$1.66M -118,349 -20%
Lord, Abbett & Co
32
Lord, Abbett & Co
New Jersey
$4.25M +$1.21M +86,372 +27%
AAA
33
Affinity Asset Advisors
New York
$4.24M +$5.61M +400,000 New
Bank of America
34
Bank of America
North Carolina
$4.04M +$4.37M +311,788 +451%
APM
35
Avidity Partners Management
Texas
$3.56M +$1.6M +114,200 +51%
Assenagon Asset Management
36
Assenagon Asset Management
Luxembourg
$3.55M +$3.66M +261,323 +355%
JP Morgan Chase
37
JP Morgan Chase
New York
$3.35M -$1.93M -137,585 -30%
Russell Investments Group
38
Russell Investments Group
United Kingdom
$3.22M +$4.26M +303,632 New
Charles Schwab
39
Charles Schwab
California
$2.97M +$140K +10,019 +4%
Walleye Capital
40
Walleye Capital
New York
$2.83M +$1.91M +136,303 +105%
Millennium Management
41
Millennium Management
New York
$2.82M -$2.79M -198,869 -43%
Goldman Sachs
42
Goldman Sachs
New York
$2.75M +$2.53M +180,313 +227%
Acadian Asset Management
43
Acadian Asset Management
Massachusetts
$2.65M -$108K -7,717 -3%
CSS
44
Cubist Systematic Strategies
Connecticut
$2.56M +$3.39M +241,684 New
UBS Group
45
UBS Group
Switzerland
$2.41M +$1.16M +83,070 +58%
PHP
46
Parkman Healthcare Partners
Connecticut
$2.16M -$998K -71,167 -26%
SCM
47
Silverarc Capital Management
Massachusetts
$2.16M +$1.45M +103,400 +103%
Squarepoint
48
Squarepoint
New York
$1.89M +$2.3M +163,745 +1,123%
WP
49
Woodline Partners
California
$1.86M +$493K +35,175 +25%
ECM
50
ExodusPoint Capital Management
New York
$1.78M +$2.35M +167,659 New
1
2
3 4 5

QURE Hedge Fund Activity: Q1 2025 in Review

141 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in uniQure (QURE) for Q1 2025, worth a combined $533M — down 28% from $736M a quarter earlier.

Buyers outnumbered sellers: 24 funds opened new QURE positions and 20 closed out — a net gain of 4 holders — while 53 added to existing stakes and 37 trimmed.

The largest buyer was RTW Investments, adding an estimated $47.1M. The largest seller was Point72 Asset Management, cutting an estimated $23M.

  • 141 institutional investors held uniQure (QURE) as of Q1 2025, up from 138 in Q4 2024.
  • Funds reported $533M of uniQure stock for Q1 2025, down 28% quarter-over-quarter.
  • 24 funds opened new uniQure positions in Q1 2025 and 20 closed out, a net change of +4 holders.
  • The largest uniQure buyer in Q1 2025 was RTW Investments, an estimated $47.1M added.
  • The largest uniQure seller in Q1 2025 was Point72 Asset Management, an estimated $23M sold.

Based on aggregated 13F filings for Q1 2025.