uniQure
QURE
218 hedge funds and large institutions have $3.23B invested in uniQure in 2025 Q3 according to their latest regulatory filings, with 96 funds opening new positions, 48 increasing their positions, 62 reducing their positions, and 20 closing their positions.
650% more funds holding in top 10
Funds holding in top 10: 2 → 15 (+13)
380% more first-time investments, than exits
New positions opened: 96 | Existing positions closed: 20
338% more capital invested
Capital invested by funds: $738M → $3.23B (+$2.49B)
52% more funds holding
Funds holding: 143 → 218 (+75)
4.2% more ownership
Funds ownership: 96.69% → 100.88% (+4.2%)
3% more call options, than puts
Call options by funds: $291M | Put options by funds: $281M
23% less repeat investments, than reductions
Existing positions increased: 48 | Existing positions reduced: 62
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Fidelity Investments
Boston,
Massachusetts
|
+$88.5M |
| 2 |
FAM
Fred Alger Management
New York
|
+$23.4M |
| 3 |
T. Rowe Price Associates
Baltimore,
Maryland
|
+$16.6M |
| 4 |
EP
Eversept Partners
New York
|
+$15.9M |
| 5 |
Jennison Associates
New York
|
+$15.6M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
VPC
Vestal Point Capital
New York
|
-$63.1M |
| 2 |
JFG
Jefferies Financial Group
New York
|
-$36.4M |
| 3 |
SI
Sofinnova Investments
Menlo Park,
California
|
-$25.8M |
| 4 |
NCM
Nantahala Capital Management
New Canaan,
Connecticut
|
-$19M |
| 5 |
IHAM
Integral Health Asset Management
New York
|
-$13.6M |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
226
Jane Street
New York
| – | -$916K | -50,430 | Closed |
|
|
CC
227
Centiva Capital
New York
| – | -$908K | -50,000 | Closed |
|
|
SFI
228
Susquehanna Fundamental Investments
Bala Cynwyd,
Pennsylvania
| – | -$537K | -38,534 | Closed |
|
|
HF
229
HRT Financial
New York
| – | -$396K | -28,420 | Closed |
|
|
EGM
230
Engineers Gate Manager
New York
| – | -$389K | -27,904 | Closed |
|
|
FFWM
231
Future Financial Wealth Management
Cincinnati,
Ohio
| – | -$55.8K | -4,000 | Closed |
|
|
PHK
232
Point72 Hong Kong
Hong Kong
| – | -$20.4K | -1,465 | Closed |
|
233
Toronto Dominion Bank
Toronto, Ontario,
Ontario, Canada
| – | -$16.7K | -1,200 | Closed |
|
|
C
234
Covestor
London,
United Kingdom
| – | -$16K | -1,183 | Closed |
|
235
National Bank of Canada
Montreal,
Quebec, Canada
| – | -$10.8K | -779 | Closed |
|
|
BIG
236
Brooklyn Investment Group
Brooklyn,
New York
| – | -$6.23K | -447 | Closed |
|
|
WSFS
237
Wilmington Savings Fund Society
Wilmington,
Delaware
| – | -$4.91K | -352 | Closed |
|
|
NS
238
NBC Securities
Birmingham,
Alabama
| – | -$1K | -3 | Closed |
|
QURE Hedge Fund Activity: Q3 2025 in Review
218 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in uniQure (QURE) for Q3 2025, worth a combined $3.23B — up 338% from $738M a quarter earlier.
Buyers outnumbered sellers: 96 funds opened new QURE positions and 20 closed out — a net gain of 76 holders — while 48 added to existing stakes and 62 trimmed.
The largest buyer was Fidelity Investments, adding an estimated $88.5M. The largest seller was Vestal Point Capital, cutting an estimated $63.1M.
- 218 institutional investors held uniQure (QURE) as of Q3 2025, up from 143 in Q2 2025.
- Funds reported $3.23B of uniQure stock for Q3 2025, up 338% quarter-over-quarter.
- 96 funds opened new uniQure positions in Q3 2025 and 20 closed out, a net change of +76 holders.
- The largest uniQure buyer in Q3 2025 was Fidelity Investments, an estimated $88.5M added.
- The largest uniQure seller in Q3 2025 was Vestal Point Capital, an estimated $63.1M sold.
Based on aggregated 13F filings for Q3 2025.