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PVLA

Palvella Therapeutics

67 hedge funds and large institutions have $133M invested in Palvella Therapeutics in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 19 increasing their positions, 9 reducing their positions, and 2 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,300% more first-time investments, than exits

New positions opened: 28 | Existing positions closed: 2

111% more repeat investments, than reductions

Existing positions increased: 19 | Existing positions reduced: 9

63% more funds holding

Funds holding: 4167 (+26)

7.79% more ownership

Funds ownership: 45.66%53.45% (+7.8%)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

7% less capital invested

Capital invested by funds: $143M → $133M (-$10.2M)

Holders
67
Holders Change
+26
Holders Change %
+63.41%
% of All Funds
0.88%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
28
Increased
19
Reduced
9
Closed
2
Calls
$268K
Puts
Net Calls
+$268K
Net Calls Change
+$214K
Name Holding Trade Value Shares
Change
Change in
Stake
FLSM
1
Frazier Life Sciences Management
California
$16.3M +$760K +32,388 +5%
SCM
2
Suvretta Capital Management
New York
$16.1M
BI
3
BVF Inc
California
$15.7M
WP
4
Woodline Partners
California
$10M +$5.9M +251,448 +130%
BlackRock
5
BlackRock
New York
$10M +$7.85M +334,294 +302%
SB
6
Samsara BioCapital
California
$7.66M -$7.97M -339,743 -50%
Millennium Management
7
Millennium Management
New York
$7.1M +$1.06M +45,152 +17%
ASP
8
Adams Street Partners
Illinois
$6.74M -$2.6M -110,680 -27%
NCM
9
Nantahala Capital Management
Connecticut
$5.64M
Geode Capital Management
10
Geode Capital Management
Massachusetts
$3.92M +$1.87M +79,787 +85%
Vanguard Group
11
Vanguard Group
Pennsylvania
$3.69M +$596K +25,376 +18%
Morgan Stanley
12
Morgan Stanley
New York
$3.06M +$2.95M +125,847 +1,270%
BOCH
13
Blue Owl Capital Holdings
New York
$2.82M -$352K -15,000 -11%
SAM
14
Sectoral Asset Management
Quebec, Canada
$2.16M +$2.24M +95,615 New
CAM
15
Clio Asset Management
Virginia
$2.06M +$2.15M +91,508 New
Goldman Sachs
16
Goldman Sachs
New York
$1.92M +$1.56M +66,276 +348%
State Street
17
State Street
Massachusetts
$1.85M +$1.64M +69,949 +580%
RA
18
Royce & Associates
New York
$1.68M +$70.5K +3,002 +4%
AIC
19
AWM Investment Company
New York
$1.56M
Renaissance Technologies
20
Renaissance Technologies
New York
$1.51M +$1.21M +51,600 +338%
JGC
21
J. Goldman & Co
New York
$1.27M +$1.32M +56,290 New
Northern Trust
22
Northern Trust
Illinois
$1.23M +$889K +37,868 +228%
Marshall Wace
23
Marshall Wace
United Kingdom
$1.11M +$440K +18,732 +62%
UOC
24
UBS O'Connor
Illinois
$992K -$110K -4,670 -10%
DCM
25
DAFNA Capital Management
California
$977K

PVLA Hedge Fund Activity: Q2 2025 in Review

67 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Palvella Therapeutics (PVLA) for Q2 2025, worth a combined $133M — down 7.1% from $143M a quarter earlier.

Buyers outnumbered sellers: 28 funds opened new PVLA positions and 2 closed out — a net gain of 26 holders — while 19 added to existing stakes and 9 trimmed.

The largest buyer was BlackRock, adding an estimated $7.85M. The largest seller was Samsara BioCapital, cutting an estimated $7.97M.

  • 67 institutional investors held Palvella Therapeutics (PVLA) as of Q2 2025, up from 41 in Q1 2025.
  • Funds reported $133M of Palvella Therapeutics stock for Q2 2025, down 7.1% quarter-over-quarter.
  • 28 funds opened new Palvella Therapeutics positions in Q2 2025 and 2 closed out, a net change of +26 holders.
  • The largest Palvella Therapeutics buyer in Q2 2025 was BlackRock, an estimated $7.85M added.
  • The largest Palvella Therapeutics seller in Q2 2025 was Samsara BioCapital, an estimated $7.97M sold.

Based on aggregated 13F filings for Q2 2025.