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PVLA

Palvella Therapeutics

41 hedge funds and large institutions have $143M invested in Palvella Therapeutics in 2025 Q1 according to their latest regulatory filings, with 15 funds opening new positions, 9 increasing their positions, 4 reducing their positions, and 7 closing their positions.

New
Increased
Maintained
Reduced
Closed

2,700% more call options, than puts

Call options by funds: $56K | Put options by funds: $2K

196% more capital invested

Capital invested by funds: $48.4M → $143M (+$95M)

125% more repeat investments, than reductions

Existing positions increased: 9 | Existing positions reduced: 4

114% more first-time investments, than exits

New positions opened: 15 | Existing positions closed: 7

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

24% more funds holding

Funds holding: 3341 (+8)

9.72% more ownership

Funds ownership: 35.95%45.66% (+9.7%)

Holders
41
Holders Change
+8
Holders Change %
+24.24%
% of All Funds
0.55%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
15
Increased
9
Reduced
4
Closed
7
Calls
$56K
Puts
$2K
Net Calls
+$54K
Net Calls Change
+$54K
Name Holding Trade Value Shares
Change
Change in
Stake
SCM
1
Suvretta Capital Management
New York
$20M
BI
2
BVF Inc
California
$19.5M
FLSM
3
Frazier Life Sciences Management
California
$19.3M +$696K +36,120 +6%
SB
4
Samsara BioCapital
California
$19M
ASP
5
Adams Street Partners
Illinois
$11.5M
Millennium Management
6
Millennium Management
New York
$7.55M +$5.2M +269,837 New
NCM
7
Nantahala Capital Management
Connecticut
$7M
WP
8
Woodline Partners
California
$5.43M +$3.74M +194,167 New
OM
9
Opaleye Management
Massachusetts
$4.82M +$3.32M +172,357 New
BOCH
10
Blue Owl Capital Holdings
New York
$3.93M -$2.12M -109,803 -44%
Vanguard Group
11
Vanguard Group
Pennsylvania
$3.87M +$2.45M +127,091 +1,121%
Susquehanna International Group
12
Susquehanna International Group
Pennsylvania
$3.2M +$2.2M +114,388 New
BlackRock
13
BlackRock
New York
$3.1M +$1.88M +97,820 +756%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$2.64M +$1.54M +79,929 +560%
RA
15
Royce & Associates
New York
$2M +$1.38M +71,514 New
AIC
16
AWM Investment Company
New York
$1.94M +$1.34M +69,416 New
UOC
17
UBS O'Connor
Illinois
$1.36M +$938K +48,664 New
DCM
18
DAFNA Capital Management
California
$1.21M -$542K -28,104 -39%
Marshall Wace
19
Marshall Wace
United Kingdom
$849K +$585K +30,345 New
SG
20
Strid Group
Pennsylvania
$818K +$563K +29,219 New
CAM
21
Cresset Asset Management
Illinois
$585K
Goldman Sachs
22
Goldman Sachs
New York
$533K +$367K +19,053 New
Toronto Dominion Bank
23
Toronto Dominion Bank
Ontario, Canada
$528K +$109K +5,661 +43%
Northern Trust
24
Northern Trust
Illinois
$466K +$321K +16,635 New
Renaissance Technologies
25
Renaissance Technologies
New York
$427K -$118K -6,113 -29%

PVLA Hedge Fund Activity: Q1 2025 in Review

41 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Palvella Therapeutics (PVLA) for Q1 2025, worth a combined $143M — up 196% from $48.4M a quarter earlier.

Buyers outnumbered sellers: 15 funds opened new PVLA positions and 7 closed out — a net gain of 8 holders — while 9 added to existing stakes and 4 trimmed.

The largest buyer was Millennium Management, opening a new position worth an estimated $5.2M. The largest seller was Blue Owl Capital Holdings, cutting an estimated $2.12M.

  • 41 institutional investors held Palvella Therapeutics (PVLA) as of Q1 2025, up from 33 in Q4 2024.
  • Funds reported $143M of Palvella Therapeutics stock for Q1 2025, up 196% quarter-over-quarter.
  • 15 funds opened new Palvella Therapeutics positions in Q1 2025 and 7 closed out, a net change of +8 holders.
  • The largest Palvella Therapeutics buyer in Q1 2025 was Millennium Management, an estimated $5.2M added.
  • The largest Palvella Therapeutics seller in Q1 2025 was Blue Owl Capital Holdings, an estimated $2.12M sold.

Based on aggregated 13F filings for Q1 2025.