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Protagonist Therapeutics

274 hedge funds and large institutions have $3.15B invested in Protagonist Therapeutics in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 86 increasing their positions, 90 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
274
Holders Change
+34
Holders Change %
+14.17%
% of All Funds
3.72%
Holding in Top 10
14
Holding in Top 10 Change
+7
Holding in Top 10 Change %
+100%
% of All Funds
0.19%
New
72
Increased
86
Reduced
90
Closed
35
Calls
$51.1M
Puts
$31.9M
Net Calls
+$19.2M
Net Calls Change
+$20M
Name Holding Trade Value Shares
Change
Shares
Change %
Simplex Trading
126
Simplex Trading
Illinois
$1.25M +$989K +20,447 +373%
JG
127
Jain Global
New York
$1.2M +$1.2M +24,867 New
GAM
128
Gotham Asset Management
New York
$1.12M +$1.12M +23,072 New
Mackenzie Financial
129
Mackenzie Financial
Ontario, Canada
$1.1M +$65.2K +1,349 +6%
YCM
130
Yousif Capital Management
Michigan
$1.08M -$28.1K -581 -3%
II
131
Inspire Investing
Idaho
$1.06M +$545K +11,279 +107%
Janus Henderson Group
132
Janus Henderson Group
United Kingdom
$1.05M
WG
133
Winton Group
United Kingdom
$1.01M -$289K -5,973 -22%
GT
134
Glenmede Trust
Pennsylvania
$999K +$566K +11,713 +131%
Comerica Bank
135
Comerica Bank
Texas
$979K -$15.3K -317 -2%
TRSOTSOK
136
Teachers Retirement System of the State of Kentucky
Kentucky
$977K
YIH
137
Y-Intercept (HK)
Hong Kong
$975K +$975K +20,169 New
Verition Fund Management
138
Verition Fund Management
Connecticut
$960K +$960K +19,847 New
CAS
139
Coppell Advisory Solutions
Texas
$947K +$947K +20,765 New
New York State Common Retirement Fund
140
New York State Common Retirement Fund
New York
$947K +$82.2K +1,700 +10%
IMRF
141
Illinois Municipal Retirement Fund
Illinois
$943K -$677K -14,000 -42%
TI
142
Tidal Investments
Wisconsin
$939K -$77.5K -1,602 -8%
CCIA
143
Campbell & Co Investment Adviser
Maryland
$920K +$920K +19,015 New
SO
144
STRS Ohio
Ohio
$919K -$218K -4,500 -19%
GC
145
Guggenheim Capital
Illinois
$914K -$8.37K -173 -0.9%
CUAMC
146
China Universal Asset Management Company
China
$908K +$297K +6,135 +49%
AG
147
Algert Global
California
$903K +$45.7K +945 +5%
Jennison Associates
148
Jennison Associates
New York
$886K +$886K +18,317 New
SRL
149
Scientech Research LLC
New Jersey
$884K +$301K +6,217 +52%
BG
150
Bellevue Group
Switzerland
$852K -$295K -6,096 -26%