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Protagonist Therapeutics

274 hedge funds and large institutions have $3.15B invested in Protagonist Therapeutics in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 86 increasing their positions, 90 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding in top 10

Funds holding in top 10:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

14% more funds holding

Funds holding: 240274 (+34)

0.29% more ownership

Funds ownership: 106.16%106.45% (+0.29%)

4% less repeat investments, than reductions

Existing positions increased: 86 | Existing positions reduced: 90

Holders
274
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
14
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$51.1M
Puts
$31.9M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Simplex Trading
126
Simplex Trading
Illinois
$1.25M
JG
127
Jain Global
New York
$1.2M
GAM
128
Gotham Asset Management
New York
$1.12M
Mackenzie Financial
129
Mackenzie Financial
Ontario, Canada
$1.1M
YCM
130
Yousif Capital Management
Michigan
$1.08M
II
131
Inspire Investing
Idaho
$1.06M
Janus Henderson Group
132
Janus Henderson Group
United Kingdom
$1.05M
WG
133
Winton Group
United Kingdom
$1.01M
GT
134
Glenmede Trust
Pennsylvania
$999K
Comerica Bank
135
Comerica Bank
Texas
$979K
TRSOTSOK
136
Teachers Retirement System of the State of Kentucky
Kentucky
$977K
YIH
137
Y-Intercept (HK)
Hong Kong
$975K
Verition Fund Management
138
Verition Fund Management
Connecticut
$960K
CAS
139
Coppell Advisory Solutions
Texas
$947K
New York State Common Retirement Fund
140
New York State Common Retirement Fund
New York
$947K
IMRF
141
Illinois Municipal Retirement Fund
Illinois
$943K
TI
142
Tidal Investments
Wisconsin
$939K
CCIA
143
Campbell & Co Investment Adviser
Maryland
$920K
SO
144
STRS Ohio
Ohio
$919K
GC
145
Guggenheim Capital
Illinois
$914K
CUAMC
146
China Universal Asset Management Company
China
$908K
AG
147
Algert Global
California
$903K
Jennison Associates
148
Jennison Associates
New York
$886K
SRL
149
Scientech Research LLC
New Jersey
$884K
BG
150
Bellevue Group
Switzerland
$852K