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Protagonist Therapeutics

316 hedge funds and large institutions have $8.3B invested in Protagonist Therapeutics in 2026 Q1 according to their latest regulatory filings, with 58 funds opening new positions, 110 increasing their positions, 102 reducing their positions, and 47 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more ownership

Funds ownership:

8% more repeat investments, than reductions

Existing positions increased: 110 | Existing positions reduced: 102

1% more funds holding

Funds holding: 313316 (+3)

23% less funds holding in top 10

Funds holding in top 10: 1310 (-3)

Holders
316
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$36.2M
Puts
$11.1M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
VAM
101
Vanguard Asset Management
$4.89M
O
102
OrbiMed
New York
$4.44M
Russell Investments Group
103
Russell Investments Group
United Kingdom
$4.26M
Thrivent Financial for Lutherans
104
Thrivent Financial for Lutherans
Minnesota
$4.13M
EC
105
Elmind Capital
New York
$4.01M
SOADOR
106
State of Alaska Department of Revenue
Alaska
$3.91M
BC
107
Birchview Capital
Vermont
$3.69M
HS
108
HighVista Strategies
Massachusetts
$3.57M
MIM
109
MetLife Investment Management
New Jersey
$3.35M
LP
110
LMR Partners
United Kingdom
$3.25M
State of Wisconsin Investment Board
111
State of Wisconsin Investment Board
Wisconsin
$3.24M
Mirae Asset Global ETFs Holdings
112
Mirae Asset Global ETFs Holdings
Hong Kong
$3.21M
Wells Fargo
113
Wells Fargo
California
$3.17M
Allspring Global Investments
114
Allspring Global Investments
North Carolina
$3.1M
IMRF
115
Illinois Municipal Retirement Fund
Illinois
$3.01M
Pathstone Holdings
116
Pathstone Holdings
New Jersey
$2.98M
EI
117
EAM Investors
California
$2.94M
GIM
118
Granahan Investment Management
Massachusetts
$2.89M
Connor, Clark & Lunn Investment Management (CC&L)
119
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$2.87M
TRSOTSOK
120
Teachers Retirement System of the State of Kentucky
Kentucky
$2.8M
LSERS
121
Louisiana State Employees Retirement System
Louisiana
$2.75M
VGA
122
Vanguard Global Advisers
Pennsylvania
$2.6M
Polen Capital Management
123
Polen Capital Management
Florida
$2.57M
ETC
124
Exchange Traded Concepts
Oklahoma
$2.51M
Calamos Advisors
125
Calamos Advisors
Illinois
$2.47M