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Protagonist Therapeutics

317 hedge funds and large institutions have $8.3B invested in Protagonist Therapeutics in 2026 Q1 according to their latest regulatory filings, with 59 funds opening new positions, 110 increasing their positions, 102 reducing their positions, and 47 closing their positions.

New
Increased
Maintained
Reduced
Closed

225% more call options, than puts

Call options by funds: $36.2M | Put options by funds: $11.1M

34% more capital invested

Capital invested by funds: $6.18B → $8.3B (+$2.12B)

26% more first-time investments, than exits

New positions opened: 59 | Existing positions closed: 47

10.28% more ownership

Funds ownership: 113.13%123.41% (+10%)

1% more funds holding

Funds holding: 313317 (+4)

8% more repeat investments, than reductions

Existing positions increased: 110 | Existing positions reduced: 102

23% less funds holding in top 10

Funds holding in top 10: 1310 (-3)

Holders
317
Holders Change
+4
Holders Change %
+1.28%
% of All Funds
3.9%
Holding in Top 10
10
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-23.08%
% of All Funds
0.12%
New
59
Increased
110
Reduced
102
Closed
47
Calls
$36.2M
Puts
$11.1M
Net Calls
+$25.1M
Net Calls Change
-$55.5M
Name Holding Trade Value Shares
Change
Change in
Stake
Prudential Financial
76
Prudential Financial
New Jersey
$10M -$1.34M -15,125 -14%
First Trust Advisors
77
First Trust Advisors
Illinois
$9.26M +$3.67M +41,404 +89%
AI
78
Axiom Investors
Connecticut
$9.01M -$354K -3,993 -4%
Victory Capital Management
79
Victory Capital Management
Texas
$8.81M +$263K +2,973 +4%
SEI Investments
80
SEI Investments
Pennsylvania
$8.77M +$4.06M +45,851 +123%
AG
81
Algert Global
California
$8.27M +$6.5M +73,380 +1,442%
SC
82
Stempoint Capital
New York
$7.65M +$1.16M +13,147 +22%
GLA
83
Great Lakes Advisors
Illinois
$7.49M -$259K -2,923 -4%
DMKJ
84
David M. Knott Jr
$6.64M -$885K -10,000 -14%
ACM
85
Atika Capital Management
New York
$6.55M -$2.12M -23,900 -28%
AllianceBernstein
86
AllianceBernstein
Tennessee
$6.44M +$50.3K +568 +0.8%
California State Teachers Retirement System (CalSTRS)
87
California State Teachers Retirement System (CalSTRS)
California
$6.18M +$942K +10,644 +22%
Bessemer Group
88
Bessemer Group
New Jersey
$5.71M +$1.42K +16 +0%
MAP
89
Moody Aldrich Partners
Massachusetts
$5.68M -$2.37M -26,730 -33%
KCA
90
KVP Capital Advisors
California
$5.59M
Nordea Investment Management
91
Nordea Investment Management
Sweden
$5.33M +$4.59M +51,821 New
EI
92
EFG International
$5.28M -$2M -22,537 -31%
IHAM
93
Integral Health Asset Management
New York
$5.27M +$4.43M +50,000 New
Northwestern Mutual Wealth Management
94
Northwestern Mutual Wealth Management
Wisconsin
$5.17M +$11.2K +126 +0.3%
Creative Planning
95
Creative Planning
Kansas
$5.06M +$595K +6,717 +16%
SAM
96
Silvercrest Asset Management
New York
$5.05M -$468K -5,286 -10%
Canada Life
97
Canada Life
Manitoba, Canada
$5M -$195K -2,200 -4%
New York State Teachers Retirement System (NYSTRS)
98
New York State Teachers Retirement System (NYSTRS)
New York
$5M -$171K -1,926 -4%
Rafferty Asset Management
99
Rafferty Asset Management
New York
$4.93M -$1.5M -16,909 -27%
AssetMark Inc
100
AssetMark Inc
California
$4.89M +$4.09M +46,157 +16,195%