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Protagonist Therapeutics

272 hedge funds and large institutions have $3.92B invested in Protagonist Therapeutics in 2025 Q2 according to their latest regulatory filings, with 51 funds opening new positions, 119 increasing their positions, 77 reducing their positions, and 49 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more capital invested

Capital invested by funds: $ → $

more ownership

Funds ownership:

more first-time investments, than exits

New positions opened: | Existing positions closed:

0% more funds holding in top 10

Funds holding in top 10: 1414 (0)

1% less funds holding

Funds holding: 274272 (-2)

12% less call options, than puts

Call options by funds: $18.4M | Put options by funds: $20.8M

Holders
272
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
14
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$18.4M
Puts
$20.8M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Citigroup
76
Citigroup
New York
$4.31M
Prudential Financial
77
Prudential Financial
New Jersey
$4.28M
SSA
78
Schonfeld Strategic Advisors
New York
$4.26M
DP
79
Diadema Partners
New Jersey
$4.21M
Royal Bank of Canada
80
Royal Bank of Canada
Ontario, Canada
$4.13M
EI
81
EAM Investors
California
$3.98M
Susquehanna International Group
82
Susquehanna International Group
Pennsylvania
$3.94M
EGI
83
EAM Global Investors
California
$3.85M
Qube Research & Technologies (QRT)
84
Qube Research & Technologies (QRT)
United Kingdom
$3.81M
AllianceBernstein
85
AllianceBernstein
Tennessee
$3.75M
PHP
86
Parkman Healthcare Partners
Connecticut
$3.4M
BCM
87
Boxer Capital Management
California
$3.32M
HS
88
HighVista Strategies
Massachusetts
$3.2M
New York State Teachers Retirement System (NYSTRS)
89
New York State Teachers Retirement System (NYSTRS)
New York
$3.08M
SAM
90
Silvercrest Asset Management
New York
$3.02M
AI
91
Axiom Investors
Connecticut
$2.83M
California State Teachers Retirement System (CalSTRS)
92
California State Teachers Retirement System (CalSTRS)
California
$2.83M
Canada Life
93
Canada Life
Manitoba, Canada
$2.78M
Capital Fund Management (CFM)
94
Capital Fund Management (CFM)
France
$2.75M
BC
95
Birchview Capital
Vermont
$2.65M
ETC
96
Exchange Traded Concepts
Oklahoma
$2.62M
Thrivent Financial for Lutherans
97
Thrivent Financial for Lutherans
Minnesota
$2.52M
SEI Investments
98
SEI Investments
Pennsylvania
$2.48M
N
99
Natixis
France
$2.32M
ACM
100
Aquatic Capital Management
Illinois
$2.32M